5TW7

Crystal structure of a GMP synthase (glutamine-hydrolyzing) from Neisseria gonorrhoeae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003921	molecular_function	GMP synthase activity
A	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006177	biological_process	GMP biosynthetic process
A	0016874	molecular_function	ligase activity
A	0046037	biological_process	GMP metabolic process
B	0000166	molecular_function	nucleotide binding
B	0003921	molecular_function	GMP synthase activity
B	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006177	biological_process	GMP biosynthetic process
B	0016874	molecular_function	ligase activity
B	0046037	biological_process	GMP metabolic process
C	0000166	molecular_function	nucleotide binding
C	0003921	molecular_function	GMP synthase activity
C	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006177	biological_process	GMP biosynthetic process
C	0016874	molecular_function	ligase activity
C	0046037	biological_process	GMP metabolic process
D	0000166	molecular_function	nucleotide binding
D	0003921	molecular_function	GMP synthase activity
D	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006177	biological_process	GMP biosynthetic process
D	0016874	molecular_function	ligase activity
D	0046037	biological_process	GMP metabolic process
E	0000166	molecular_function	nucleotide binding
E	0003921	molecular_function	GMP synthase activity
E	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
E	0005524	molecular_function	ATP binding
E	0005829	cellular_component	cytosol
E	0006164	biological_process	purine nucleotide biosynthetic process
E	0006177	biological_process	GMP biosynthetic process
E	0016874	molecular_function	ligase activity
E	0046037	biological_process	GMP metabolic process
F	0000166	molecular_function	nucleotide binding
F	0003921	molecular_function	GMP synthase activity
F	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
F	0005524	molecular_function	ATP binding
F	0005829	cellular_component	cytosol
F	0006164	biological_process	purine nucleotide biosynthetic process
F	0006177	biological_process	GMP biosynthetic process
F	0016874	molecular_function	ligase activity
F	0046037	biological_process	GMP metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue MG E 601

Chain	Residue
E	ILE497
E	VAL500
E	ILE503
E	HOH809
E	HOH818

---

site_id	AC2
Number of Residues	5
Details	binding site for residue MG F 601

Chain	Residue
F	HOH851
F	ILE497
F	VAL500
F	ILE503
F	HOH796

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1152
Details	Domain: {"description":"Glutamine amidotransferase type-1","evidences":[{"source":"HAMAP-Rule","id":"MF_00344","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00344","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00344","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00344","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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