5TVY
Computationally Designed Fentanyl Binder - Fen49
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0031176 | molecular_function | endo-1,4-beta-xylanase activity |
| A | 0045493 | biological_process | xylan catabolic process |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0031176 | molecular_function | endo-1,4-beta-xylanase activity |
| B | 0045493 | biological_process | xylan catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue XPE A 201 |
| Chain | Residue |
| A | TYR5 |
| A | HOH328 |
| A | HOH435 |
| A | HOH530 |
| A | HOH533 |
| A | HOH551 |
| A | LEU7 |
| A | PHE9 |
| A | TRP63 |
| A | TYR80 |
| A | THR91 |
| A | PRO116 |
| A | ILE118 |
| A | TYR166 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue XPE B 201 |
| Chain | Residue |
| B | TYR5 |
| B | LEU7 |
| B | PHE9 |
| B | SER35 |
| B | TRP63 |
| B | TRP71 |
| B | TYR80 |
| B | TRP90 |
| B | THR91 |
| B | SER117 |
| B | ILE118 |
| B | TYR166 |
| B | TYR174 |
| B | HOH304 |
| B | HOH334 |
| B | HOH471 |
| B | HOH483 |
| B | HOH490 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU10062","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"7911679","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10063","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
