5TUI
Crystal structure of tetracycline destructase Tet(50) in complex with chlortetracycline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0071949 | molecular_function | FAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 401 |
| Chain | Residue |
| A | SER201 |
| A | ASN202 |
| A | HIS203 |
| A | LYS204 |
| A | HOH684 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HOH598 |
| A | THR280 |
| A | GLY282 |
| A | HOH558 |
| A | HOH586 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | LYS57 |
| A | GLY60 |
| A | ILE61 |
| A | TYR62 |
| A | ASP63 |
| A | HOH516 |
| site_id | AC4 |
| Number of Residues | 29 |
| Details | binding site for residue FAD A 404 |
| Chain | Residue |
| A | ILE10 |
| A | GLY11 |
| A | VAL12 |
| A | GLY13 |
| A | VAL14 |
| A | ALA15 |
| A | GLU34 |
| A | LYS35 |
| A | GLN44 |
| A | ALA45 |
| A | LEU46 |
| A | ASP47 |
| A | ARG105 |
| A | ALA155 |
| A | ASP156 |
| A | TYR267 |
| A | GLY288 |
| A | ASP289 |
| A | PRO296 |
| A | GLY299 |
| A | GLY301 |
| A | ASN302 |
| A | HOH510 |
| A | HOH537 |
| A | HOH540 |
| A | HOH541 |
| A | HOH577 |
| A | HOH589 |
| A | HOH627 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 401 |
| Chain | Residue |
| B | GLY282 |
| B | HOH538 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | HIS54 |
| B | LYS57 |
| B | ASN248 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| A | HIS240 |
| B | PRO187 |
| B | TYR189 |
| B | ARG259 |
| site_id | AC8 |
| Number of Residues | 33 |
| Details | binding site for residue FAD B 404 |
| Chain | Residue |
| B | ILE10 |
| B | GLY11 |
| B | VAL12 |
| B | GLY13 |
| B | VAL14 |
| B | ALA15 |
| B | GLU34 |
| B | LYS35 |
| B | SER36 |
| B | GLN44 |
| B | ALA45 |
| B | LEU46 |
| B | ASP47 |
| B | ARG105 |
| B | ALA155 |
| B | ASP156 |
| B | TYR267 |
| B | GLY288 |
| B | ASP289 |
| B | PRO296 |
| B | GLY299 |
| B | GLY301 |
| B | ASN302 |
| B | CTC405 |
| B | HOH506 |
| B | HOH550 |
| B | HOH551 |
| B | HOH587 |
| B | HOH589 |
| B | HOH593 |
| B | HOH605 |
| B | HOH609 |
| B | HOH652 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | binding site for residue CTC B 405 |
| Chain | Residue |
| B | FAD404 |
| B | HOH513 |
| B | HOH594 |
| B | ASP47 |
| B | ARG49 |
| B | GLY94 |
| B | PHE95 |
| B | LEU198 |
| B | LEU205 |
| B | GLY220 |
| B | PHE221 |
| B | MET222 |
| B | PRO296 |
| B | LEU297 |
| B | GLY299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5TUE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TUF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TUI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"5TUE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TUF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
