5TTP

Cryo-EM structure of MsbA-nanodisc with ADP-vanadate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006869	biological_process	lipid transport
A	0008289	molecular_function	lipid binding
A	0008559	molecular_function	ABC-type xenobiotic transporter activity
A	0015437	molecular_function	lipopolysaccharide floppase activity
A	0015920	biological_process	lipopolysaccharide transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
A	0034204	biological_process	lipid translocation
A	0042802	molecular_function	identical protein binding
A	0042908	biological_process	xenobiotic transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
A	1990199	cellular_component	MsbA transporter complex
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006869	biological_process	lipid transport
B	0008289	molecular_function	lipid binding
B	0008559	molecular_function	ABC-type xenobiotic transporter activity
B	0015437	molecular_function	lipopolysaccharide floppase activity
B	0015920	biological_process	lipopolysaccharide transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
B	0034204	biological_process	lipid translocation
B	0042802	molecular_function	identical protein binding
B	0042908	biological_process	xenobiotic transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
B	1990199	cellular_component	MsbA transporter complex

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRIAIARAL

Chain	Residue	Details
A	LEU481-LEU495

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	282
Details	TRANSMEM: Helical => ECO:0000255|HAMAP-Rule:MF_01703

Chain	Residue	Details
A	LEU16-LEU36
B	VAL275-MET295
A	SER140-TYR162
A	LEU167-SER186
B	SER140-TYR162
B	LEU167-SER186
A	VAL63-TYR83
A	ILE153-VAL173
A	PRO253-PRO273
A	VAL275-MET295
B	LEU16-LEU36
B	VAL63-TYR83
B	ILE153-VAL173
B	PRO253-PRO273

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01703

Chain	Residue	Details
A	GLY376
B	GLY376

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