Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| A | 0039694 | biological_process | viral RNA genome replication |
| B | 0003723 | molecular_function | RNA binding |
| B | 0003968 | molecular_function | RNA-directed RNA polymerase activity |
| B | 0039694 | biological_process | viral RNA genome replication |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue 23E A 601 |
| Chain | Residue |
| A | ALA396 |
| B | 23E601 |
| B | HOH809 |
| A | LEU492 |
| A | GLY493 |
| A | VAL494 |
| A | PRO495 |
| A | ARG498 |
| A | VAL499 |
| A | ARG503 |
| A | HOH929 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue 7HH A 602 |
| Chain | Residue |
| A | PHE193 |
| A | PRO197 |
| A | ARG200 |
| A | SER288 |
| A | GLY317 |
| A | CYS366 |
| A | SER368 |
| A | LEU384 |
| A | GLY410 |
| A | ASN411 |
| A | MET414 |
| A | TYR415 |
| A | GLN446 |
| A | TYR448 |
| A | SER556 |
| A | HOH773 |
| A | HOH812 |
| A | HOH855 |
| A | HOH918 |
| A | HOH945 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 603 |
| Chain | Residue |
| A | SER84 |
| A | VAL85 |
| A | ARG120 |
| A | HOH717 |
| A | HOH800 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 604 |
| Chain | Residue |
| A | ARG48 |
| A | LYS51 |
| A | ARG222 |
| A | CYS223 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 605 |
| Chain | Residue |
| A | HIS374 |
| A | SER476 |
| A | GLY516 |
| A | ARG517 |
| A | HOH742 |
| A | HOH856 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 606 |
| Chain | Residue |
| A | PRO496 |
| A | LEU497 |
| A | ARG498 |
| A | ARG570 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 607 |
| Chain | Residue |
| A | SER371 |
| A | SER478 |
| A | GLY480 |
| A | LYS523 |
| A | HOH770 |
| A | HOH824 |
| A | HOH900 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue 23E B 601 |
| Chain | Residue |
| A | ALA400 |
| A | ARG401 |
| A | HIS428 |
| A | 23E601 |
| A | HOH719 |
| B | ALA396 |
| B | LEU492 |
| B | GLY493 |
| B | VAL494 |
| B | PRO495 |
| B | ARG498 |
| B | VAL499 |
| B | ARG503 |
| B | HOH809 |
| B | HOH936 |
| site_id | AC9 |
| Number of Residues | 18 |
| Details | binding site for residue 7HH B 602 |
| Chain | Residue |
| B | PHE193 |
| B | PRO197 |
| B | ARG200 |
| B | SER288 |
| B | GLY317 |
| B | CYS366 |
| B | SER368 |
| B | GLY410 |
| B | ASN411 |
| B | MET414 |
| B | TYR415 |
| B | GLN446 |
| B | TYR448 |
| B | SER556 |
| B | HOH753 |
| B | HOH764 |
| B | HOH863 |
| B | HOH882 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 603 |
| Chain | Residue |
| B | SER84 |
| B | VAL85 |
| B | ARG120 |
| B | HOH786 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 604 |
| Chain | Residue |
| B | GLY516 |
| B | ARG517 |
| B | HOH956 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 605 |
| Chain | Residue |
| B | ARG380 |
| A | SER1 |
| B | LYS379 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 606 |
| Chain | Residue |
| B | HIS475 |
| B | SER476 |
| B | HOH906 |
| B | HOH952 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 607 |
| Chain | Residue |
| B | ARG48 |
| B | LYS51 |
| B | THR221 |
| B | ARG222 |
| B | CYS223 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 236 |
| Details | Domain: {"description":"RdRp catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00539","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P26663","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by host","evidences":[{"source":"UniProtKB","id":"P26662","evidenceCode":"ECO:0000250"}]} |
