5TQP

LIPOXYGENASE-1 (SOYBEAN) I553G MUTANT AT 300K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0016165	molecular_function	linoleate 13S-lipoxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
A	0019395	biological_process	fatty acid oxidation
A	0031408	biological_process	oxylipin biosynthetic process
A	0034440	biological_process	lipid oxidation
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity
A	0102299	molecular_function	linolenate 9R-lipoxygenase activity
B	0005506	molecular_function	iron ion binding
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0016165	molecular_function	linoleate 13S-lipoxygenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016702	molecular_function	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
B	0019395	biological_process	fatty acid oxidation
B	0031408	biological_process	oxylipin biosynthetic process
B	0034440	biological_process	lipid oxidation
B	0046872	molecular_function	metal ion binding
B	0051213	molecular_function	dioxygenase activity
B	0102299	molecular_function	linolenate 9R-lipoxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue FE A 901

Chain	Residue
A	HIS499
A	HIS504
A	HIS690
A	ASN694
A	ILE839
A	HOH1030

---

site_id	AC2
Number of Residues	6
Details	binding site for residue FE B 901

Chain	Residue
B	ASN694
B	ILE839
B	HOH1017
B	HIS499
B	HIS504
B	HIS690

---

Functional Information from PROSITE/UniProt

site_id	PS00081
Number of Residues	11
Details	LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. LHPIyKLLtPH

Chain	Residue	Details
A	LEU521-HIS531

---

site_id	PS00711
Number of Residues	15
Details	LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HQlmsHwLNTHAAmE

Chain	Residue	Details
A	HIS494-GLU508

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	44
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00726","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8502991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2SBL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"8502991","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2SBL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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