Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0009072 | biological_process | aromatic amino acid metabolic process |
A | 0016714 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue FE A 501 |
Chain | Residue |
A | HIS272 |
A | HIS277 |
A | GLU317 |
A | TRS502 |
site_id | AC2 |
Number of Residues | 12 |
Details | binding site for residue TRS A 502 |
Chain | Residue |
A | GLU273 |
A | HIS277 |
A | TYR312 |
A | GLU317 |
A | FE501 |
A | 7H5505 |
A | HOH645 |
A | TYR235 |
A | PHE241 |
A | PHE250 |
A | PRO268 |
A | HIS272 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue CCN A 503 |
Chain | Residue |
A | ILE171 |
A | ASN210 |
A | ILE211 |
A | GLN213 |
A | HOH715 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue CCN A 504 |
Chain | Residue |
A | GLU292 |
A | MET386 |
A | ARG387 |
A | THR390 |
A | HOH655 |
A | HOH699 |
A | HOH765 |
site_id | AC5 |
Number of Residues | 22 |
Details | binding site for residue 7H5 A 505 |
Chain | Residue |
A | TYR235 |
A | LEU236 |
A | PRO238 |
A | PHE241 |
A | LEU242 |
A | ARG257 |
A | TYR264 |
A | THR265 |
A | PRO266 |
A | GLU267 |
A | PRO268 |
A | HIS272 |
A | ALA309 |
A | TYR312 |
A | GLU317 |
A | SER336 |
A | SER337 |
A | CYS364 |
A | ILE366 |
A | TRS502 |
A | HOH637 |
A | HOH724 |
Functional Information from PROSITE/UniProt
site_id | PS00367 |
Number of Residues | 12 |
Details | BH4_AAA_HYDROXYL_1 Biopterin-dependent aromatic amino acid hydroxylases signature. PDtcHELLGHVP |
Chain | Residue | Details |
A | PRO268-PRO279 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR235 | |
A | ARG257 | |
A | THR265 | |
A | SER336 | |
A | ILE366 | |
Chain | Residue | Details |
A | HIS272 | |
A | HIS277 | |
A | GLU317 | |