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5TNL

Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (S)-1,2-Epoxyhexane hydrolysis intermediate

Functional Information from GO Data
ChainGOidnamespacecontents
A0004301molecular_functionepoxide hydrolase activity
A0005576cellular_componentextracellular region
A0043657cellular_componenthost cell
B0004301molecular_functionepoxide hydrolase activity
B0005576cellular_componentextracellular region
B0043657cellular_componenthost cell
C0004301molecular_functionepoxide hydrolase activity
C0005576cellular_componentextracellular region
C0043657cellular_componenthost cell
D0004301molecular_functionepoxide hydrolase activity
D0005576cellular_componentextracellular region
D0043657cellular_componenthost cell
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue 7FB A 401
ChainResidue
AHIS177
APHE178
AHIS207
ATYR239
AHIS297

site_idAC2
Number of Residues5
Detailsbinding site for residue 7FB B 401
ChainResidue
BHIS297
BHIS177
BPHE178
BHIS207
BTYR239

site_idAC3
Number of Residues5
Detailsbinding site for residue 7FB C 401
ChainResidue
CHIS177
CPHE178
CHIS207
CTYR239
CHIS297

site_idAC4
Number of Residues5
Detailsbinding site for residue 7FB D 401
ChainResidue
DHIS177
DPHE178
DHIS207
DTYR239
DHIS297

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PDB entries from 2026-05-27

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