5TN8
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with (E)-4'-hydroxy-3-((hydroxyiminio)methyl)-[1,1'-biphenyl]-4-olate
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | binding site for residue 7G3 A 601 |
Chain | Residue |
A | MET343 |
A | LEU525 |
A | HOH711 |
A | GLU353 |
A | LEU387 |
A | LEU391 |
A | ARG394 |
A | MET421 |
A | ILE424 |
A | GLY521 |
A | HIS524 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue 7G3 B 601 |
Chain | Residue |
B | GLU353 |
B | LEU387 |
B | MET388 |
B | MET421 |
B | HIS524 |
B | LEU525 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE |
Chain | Residue | Details |
A | GLU353 | |
A | ARG394 | |
A | HIS524 | |
B | GLU353 | |
B | ARG394 | |
B | HIS524 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
Chain | Residue | Details |
A | SER537 | |
B | SER537 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
Chain | Residue | Details |
A | CYS447 | |
B | CYS447 |