5TN6
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Spiro BC-estradiol, (1S,1'S,3a'S,7a'S)-7a'-methyl-1',2,2',3,3',3a',4',6',7',7a'-decahydro-1,5'-spirobi[indene]-1',5-diol
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue 7G1 A 601 |
| Chain | Residue |
| A | LEU346 |
| A | LEU525 |
| A | LEU349 |
| A | GLU353 |
| A | LEU387 |
| A | MET388 |
| A | ARG394 |
| A | PHE404 |
| A | MET421 |
| A | HIS524 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue 7G1 B 601 |
| Chain | Residue |
| B | GLU353 |
| B | MET388 |
| B | ARG394 |
| B | MET421 |
| B | HIS524 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER537 | |
| B | SER537 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS447 | |
| B | CYS447 | |
