5TN6
Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with the Spiro BC-estradiol, (1S,1'S,3a'S,7a'S)-7a'-methyl-1',2,2',3,3',3a',4',6',7',7a'-decahydro-1,5'-spirobi[indene]-1',5-diol
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue 7G1 A 601 |
Chain | Residue |
A | LEU346 |
A | LEU525 |
A | LEU349 |
A | GLU353 |
A | LEU387 |
A | MET388 |
A | ARG394 |
A | PHE404 |
A | MET421 |
A | HIS524 |
site_id | AC2 |
Number of Residues | 5 |
Details | binding site for residue 7G1 B 601 |
Chain | Residue |
B | GLU353 |
B | MET388 |
B | ARG394 |
B | MET421 |
B | HIS524 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU353 | |
A | ARG394 | |
A | HIS524 | |
B | GLU353 | |
B | ARG394 | |
B | HIS524 | |
Chain | Residue | Details |
A | SER537 | |
B | SER537 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
Chain | Residue | Details |
A | CYS447 | |
B | CYS447 | |