5TL4

Crystal structure of Sphingomonas paucimobilis aryl O-demethylase LigM

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008168	molecular_function	methyltransferase activity
A	0032259	biological_process	methylation
A	0046274	biological_process	lignin catabolic process
B	0008168	molecular_function	methyltransferase activity
B	0032259	biological_process	methylation
B	0046274	biological_process	lignin catabolic process
C	0008168	molecular_function	methyltransferase activity
C	0032259	biological_process	methylation
C	0046274	biological_process	lignin catabolic process
D	0008168	molecular_function	methyltransferase activity
D	0032259	biological_process	methylation
D	0046274	biological_process	lignin catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue CL A 501

Chain	Residue
A	MET61
A	ARG122
A	HOH611
A	HOH731

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site_id	AC2
Number of Residues	2
Details	binding site for residue NA A 502

Chain	Residue
A	ASN81
A	LYS92

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site_id	AC3
Number of Residues	1
Details	binding site for residue NH4 A 503

Chain	Residue
A	HOH1025

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site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 504

Chain	Residue
A	HOH617
A	HOH651
A	HOH809
A	HOH953
A	HOH1039
A	SER291
A	VAL293

---

site_id	AC5
Number of Residues	5
Details	binding site for residue CL B 501

Chain	Residue
B	MET61
B	ARG122
B	HOH607
B	HOH615
B	HOH998

---

site_id	AC6
Number of Residues	8
Details	binding site for residue GOL B 502

Chain	Residue
B	SER291
B	PHE292
B	VAL293
B	HOH601
B	HOH747
B	HOH844
B	HOH935
B	HOH974

---

site_id	AC7
Number of Residues	4
Details	binding site for residue CL C 501

Chain	Residue
C	MET61
C	ARG122
C	HOH611
C	HOH691

---

site_id	AC8
Number of Residues	3
Details	binding site for residue CL C 502

Chain	Residue
C	ASN81
C	LYS92
C	HOH1263

---

site_id	AC9
Number of Residues	1
Details	binding site for residue NA C 503

Chain	Residue
C	HOH882

---

site_id	AD1
Number of Residues	8
Details	binding site for residue GOL C 504

Chain	Residue
C	SER291
C	PHE292
C	VAL293
C	HOH607
C	HOH695
C	HOH827
C	HOH911
C	HOH1005

---

site_id	AD2
Number of Residues	4
Details	binding site for residue CL D 501

Chain	Residue
D	MET61
D	ARG122
D	HOH646
D	HOH711

---

site_id	AD3
Number of Residues	4
Details	binding site for residue NA D 502

Chain	Residue
D	GLU19
D	ARG22
D	HOH997
D	HOH1016

---

site_id	AD4
Number of Residues	3
Details	binding site for residue NA D 503

Chain	Residue
D	ASN81
D	LYS92
D	HOH795

---

site_id	AD5
Number of Residues	8
Details	binding site for residue GOL D 504

Chain	Residue
D	SER291
D	PHE292
D	VAL293
D	HOH614
D	HOH642
D	HOH774
D	HOH896
D	HOH1002

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	40
Details	BINDING: BINDING => ECO:0000269|PubMed:28429420

Chain	Residue	Details
A	TYR31
A	TRP256
B	TYR31
B	GLN57
B	HIS60
B	GLN93
B	VAL120
B	ARG122
B	GLN165
B	GLU215
B	TYR247
A	GLN57
B	TRP256
C	TYR31
C	GLN57
C	HIS60
C	GLN93
C	VAL120
C	ARG122
C	GLN165
C	GLU215
C	TYR247
A	HIS60
C	TRP256
D	TYR31
D	GLN57
D	HIS60
D	GLN93
D	VAL120
D	ARG122
D	GLN165
D	GLU215
D	TYR247
A	GLN93
D	TRP256
A	VAL120
A	ARG122
A	GLN165
A	GLU215
A	TYR247

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Important for activity => ECO:0000305|PubMed:28429420

Chain	Residue	Details
A	HIS60
B	HIS60
C	HIS60
D	HIS60

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	SITE: Important for activity => ECO:0000305|PubMed:28373573, ECO:0000305|PubMed:28429420

Chain	Residue	Details
A	TYR247
B	TYR247
C	TYR247
D	TYR247

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