5TII

Comprehensive Analysis of a Novel Ketoreductase for Pentangular Polyphenol Biosynthesis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0006629	biological_process	lipid metabolic process
A	0032787	biological_process	monocarboxylic acid metabolic process
B	0000166	molecular_function	nucleotide binding
B	0006629	biological_process	lipid metabolic process
B	0032787	biological_process	monocarboxylic acid metabolic process
C	0000166	molecular_function	nucleotide binding
C	0006629	biological_process	lipid metabolic process
C	0032787	biological_process	monocarboxylic acid metabolic process
D	0000166	molecular_function	nucleotide binding
D	0006629	biological_process	lipid metabolic process
D	0032787	biological_process	monocarboxylic acid metabolic process
E	0000166	molecular_function	nucleotide binding
E	0006629	biological_process	lipid metabolic process
E	0032787	biological_process	monocarboxylic acid metabolic process
F	0000166	molecular_function	nucleotide binding
F	0006629	biological_process	lipid metabolic process
F	0032787	biological_process	monocarboxylic acid metabolic process
G	0000166	molecular_function	nucleotide binding
G	0006629	biological_process	lipid metabolic process
G	0032787	biological_process	monocarboxylic acid metabolic process
H	0000166	molecular_function	nucleotide binding
H	0006629	biological_process	lipid metabolic process
H	0032787	biological_process	monocarboxylic acid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue NDP E 301

Chain	Residue
E	GLY16
E	ALA66
E	ASP67
E	ASN94
E	ALA95
E	GLY96
E	VAL97
E	ILE142
E	GLY143
E	SER144
E	TYR157
E	GLY17
E	LYS161
E	GLY188
E	VAL189
E	VAL190
E	SER18
E	ARG19
E	GLY20
E	VAL21
E	TYR40
E	ARG41
E	GLU42

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site_id	AC2
Number of Residues	18
Details	binding site for residue NDP B 301

Chain	Residue
B	GLY16
B	SER18
B	ARG19
B	VAL21
B	TYR40
B	ARG41
B	GLU42
B	ALA66
B	ASP67
B	ASN94
B	GLY96
B	VAL97
B	ILE142
B	TYR157
B	LYS161
B	GLY188
B	VAL190
B	HOH402

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site_id	AC3
Number of Residues	21
Details	binding site for residue NDP F 301

Chain	Residue
F	GLY16
F	SER18
F	ARG19
F	GLY20
F	VAL21
F	TYR40
F	ARG41
F	GLU42
F	ASP67
F	ASN94
F	GLY96
F	VAL97
F	ILE142
F	GLY143
F	SER144
F	TYR157
F	LYS161
F	GLY188
F	VAL190
F	THR192
F	HOH419

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Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. SkssevgiplRahYTATKHALrGLTrSLA

Chain	Residue	Details
A	SER144-ALA172

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