5TI1
Crystal Structure of Fumarylacetoacetate hydrolase from Burkholderia xenovorans LB400
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004334 | molecular_function | fumarylacetoacetase activity |
| A | 0006559 | biological_process | L-phenylalanine catabolic process |
| A | 0006572 | biological_process | tyrosine catabolic process |
| A | 0009072 | biological_process | aromatic amino acid metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902000 | biological_process | homogentisate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004334 | molecular_function | fumarylacetoacetase activity |
| B | 0006559 | biological_process | L-phenylalanine catabolic process |
| B | 0006572 | biological_process | tyrosine catabolic process |
| B | 0009072 | biological_process | aromatic amino acid metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 1902000 | biological_process | homogentisate catabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004334 | molecular_function | fumarylacetoacetase activity |
| C | 0006559 | biological_process | L-phenylalanine catabolic process |
| C | 0006572 | biological_process | tyrosine catabolic process |
| C | 0009072 | biological_process | aromatic amino acid metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 1902000 | biological_process | homogentisate catabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004334 | molecular_function | fumarylacetoacetase activity |
| D | 0006559 | biological_process | L-phenylalanine catabolic process |
| D | 0006572 | biological_process | tyrosine catabolic process |
| D | 0009072 | biological_process | aromatic amino acid metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 1902000 | biological_process | homogentisate catabolic process |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004334 | molecular_function | fumarylacetoacetase activity |
| E | 0006559 | biological_process | L-phenylalanine catabolic process |
| E | 0006572 | biological_process | tyrosine catabolic process |
| E | 0009072 | biological_process | aromatic amino acid metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 1902000 | biological_process | homogentisate catabolic process |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004334 | molecular_function | fumarylacetoacetase activity |
| F | 0006559 | biological_process | L-phenylalanine catabolic process |
| F | 0006572 | biological_process | tyrosine catabolic process |
| F | 0009072 | biological_process | aromatic amino acid metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 1902000 | biological_process | homogentisate catabolic process |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0004334 | molecular_function | fumarylacetoacetase activity |
| G | 0006559 | biological_process | L-phenylalanine catabolic process |
| G | 0006572 | biological_process | tyrosine catabolic process |
| G | 0009072 | biological_process | aromatic amino acid metabolic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0046872 | molecular_function | metal ion binding |
| G | 1902000 | biological_process | homogentisate catabolic process |
| H | 0003824 | molecular_function | catalytic activity |
| H | 0004334 | molecular_function | fumarylacetoacetase activity |
| H | 0006559 | biological_process | L-phenylalanine catabolic process |
| H | 0006572 | biological_process | tyrosine catabolic process |
| H | 0009072 | biological_process | aromatic amino acid metabolic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0046872 | molecular_function | metal ion binding |
| H | 1902000 | biological_process | homogentisate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 501 |
| Chain | Residue |
| A | ASP145 |
| A | GLU218 |
| A | GLU220 |
| A | ASP252 |
| A | LYS272 |
| A | HOH784 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue NA A 502 |
| Chain | Residue |
| A | ALA275 |
| A | THR276 |
| A | ASP252 |
| A | TRP253 |
| A | LYS272 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 501 |
| Chain | Residue |
| B | ASP145 |
| B | GLU218 |
| B | GLU220 |
| B | ASP252 |
| B | LYS272 |
| B | HOH766 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 502 |
| Chain | Residue |
| B | ASP252 |
| B | TRP253 |
| B | LYS272 |
| B | ALA275 |
| B | THR276 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 501 |
| Chain | Residue |
| C | ASP145 |
| C | GLU218 |
| C | GLU220 |
| C | ASP252 |
| C | HOH753 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 502 |
| Chain | Residue |
| C | ASP252 |
| C | TRP253 |
| C | LYS272 |
| C | ALA275 |
| C | THR276 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 C 503 |
| Chain | Residue |
| C | PHE160 |
| C | ARG161 |
| C | HOH674 |
| C | HOH792 |
| D | PRO265 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 501 |
| Chain | Residue |
| D | ASP145 |
| D | GLU218 |
| D | GLU220 |
| D | ASP252 |
| D | LYS272 |
| D | HOH762 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 502 |
| Chain | Residue |
| D | ASP252 |
| D | TRP253 |
| D | LYS272 |
| D | ALA275 |
| D | THR276 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 D 503 |
| Chain | Residue |
| D | ASP55 |
| D | ARG128 |
| D | HOH619 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 D 504 |
| Chain | Residue |
| C | PRO265 |
| D | TYR147 |
| D | GLY157 |
| D | PHE160 |
| D | ARG161 |
| D | TYR263 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 501 |
| Chain | Residue |
| E | ASP145 |
| E | GLU218 |
| E | GLU220 |
| E | ASP252 |
| E | LYS272 |
| E | HOH750 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue NA E 502 |
| Chain | Residue |
| E | ASP252 |
| E | TRP253 |
| E | LYS272 |
| E | ALA275 |
| E | THR276 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 E 503 |
| Chain | Residue |
| E | ARG161 |
| E | HOH867 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue MG F 501 |
| Chain | Residue |
| F | ASP145 |
| F | GLU218 |
| F | GLU220 |
| F | ASP252 |
| F | LYS272 |
| F | HOH797 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue NA F 502 |
| Chain | Residue |
| F | ASP252 |
| F | TRP253 |
| F | LYS272 |
| F | ALA275 |
| F | THR276 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 F 503 |
| Chain | Residue |
| D | SER4 |
| D | SER5 |
| F | ARG307 |
| F | HOH602 |
| F | HOH609 |
| F | HOH758 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 F 504 |
| Chain | Residue |
| F | PHE160 |
| F | ARG161 |
| F | HOH603 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue MG G 501 |
| Chain | Residue |
| G | ASP145 |
| G | GLU218 |
| G | GLU220 |
| G | ASP252 |
| G | LYS272 |
| G | HOH792 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue NA G 502 |
| Chain | Residue |
| G | ALA275 |
| G | THR276 |
| G | ASP252 |
| G | TRP253 |
| G | LYS272 |
| site_id | AE3 |
| Number of Residues | 6 |
| Details | binding site for residue NO3 G 503 |
| Chain | Residue |
| G | TYR263 |
| G | VAL264 |
| G | PRO265 |
| G | HOH708 |
| H | TYR263 |
| H | PRO265 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue MG H 501 |
| Chain | Residue |
| H | ASP145 |
| H | GLU218 |
| H | GLU220 |
| H | ASP252 |
| H | LYS272 |
| H | HOH775 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue NA H 502 |
| Chain | Residue |
| H | ASP252 |
| H | TRP253 |
| H | LYS272 |
| H | ALA275 |
| H | THR276 |
| site_id | AE6 |
| Number of Residues | 1 |
| Details | binding site for residue NO3 H 503 |
| Chain | Residue |
| H | ARG161 |
