Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5THK

Crystal Structure of a Putative Dehydrogenase from Burkholderia cenocepacia with bound NADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0016491	molecular_function	oxidoreductase activity
E	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0016491	molecular_function	oxidoreductase activity
F	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0016491	molecular_function	oxidoreductase activity
G	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0016491	molecular_function	oxidoreductase activity
H	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	36
Details	binding site for residue NAP A 300

Chain	Residue
A	GLY15
A	ASP69
A	LEU70
A	THR71
A	THR96
A	VAL97
A	GLY98
A	VAL145
A	TYR159
A	LYS163
A	PRO189
A	LYS18
A	GLY190
A	PRO191
A	MET192
A	THR194
A	PHE196
A	PHE197
A	HOH415
A	HOH422
A	HOH425
A	HOH447
A	ASN19
A	HOH449
A	HOH493
A	HOH495
A	HOH563
A	HOH586
A	HOH597
A	HOH600
A	LEU20
A	HIS39
A	ASN41
A	SER42
A	SER45
A	ALA68

site_id	AC2
Number of Residues	37
Details	binding site for residue NAP B 300

Chain	Residue
B	GLY15
B	LYS18
B	ASN19
B	LEU20
B	HIS39
B	ASN41
B	SER42
B	SER45
B	ALA68
B	ASP69
B	LEU70
B	THR71
B	THR96
B	VAL97
B	GLY98
B	VAL145
B	TYR159
B	LYS163
B	PRO189
B	GLY190
B	PRO191
B	MET192
B	THR194
B	PHE196
B	PHE197
B	HOH401
B	HOH432
B	HOH440
B	HOH446
B	HOH451
B	HOH498
B	HOH529
B	HOH532
B	HOH537
B	HOH568
B	HOH595
B	HOH622

site_id	AC3
Number of Residues	34
Details	binding site for residue NAP C 301

Chain	Residue
C	HOH436
C	HOH516
C	HOH525
C	HOH535
C	HOH559
C	HOH563
C	HOH581
C	HOH599
C	GLY15
C	LYS18
C	ASN19
C	LEU20
C	HIS39
C	ASN41
C	SER42
C	SER45
C	ASP69
C	LEU70
C	THR71
C	THR96
C	VAL97
C	GLY98
C	VAL145
C	TYR159
C	LYS163
C	PRO189
C	GLY190
C	MET192
C	THR194
C	PHE196
C	PHE197
C	HOH402
C	HOH407
C	HOH428

site_id	AC4
Number of Residues	3
Details	binding site for residue MG C 302

Chain	Residue
C	GLY30
C	1PE303
D	GLY30

site_id	AC5
Number of Residues	9
Details	binding site for residue 1PE C 303

Chain	Residue
C	GLY30
C	HIS31
C	GLY32
C	ALA59
C	MG302
D	GLY30
D	HIS31
D	GLY32
D	ALA59

site_id	AC6
Number of Residues	34
Details	binding site for residue NAP D 300

Chain	Residue
D	GLY15
D	LYS18
D	ASN19
D	LEU20
D	HIS39
D	ASN41
D	SER42
D	SER45
D	ALA68
D	ASP69
D	LEU70
D	THR71
D	THR96
D	VAL97
D	GLY98
D	VAL145
D	TYR159
D	LYS163
D	PRO189
D	GLY190
D	MET192
D	THR194
D	PHE196
D	PHE197
D	HOH401
D	HOH414
D	HOH442
D	HOH469
D	HOH490
D	HOH545
D	HOH547
D	HOH572
D	HOH574
D	HOH575

site_id	AC7
Number of Residues	34
Details	binding site for residue NAP E 300

Chain	Residue
E	GLY15
E	LYS18
E	ASN19
E	LEU20
E	HIS39
E	ASN41
E	SER42
E	SER45
E	ASP69
E	LEU70
E	THR71
E	THR96
E	VAL97
E	GLY98
E	VAL145
E	TYR159
E	LYS163
E	PRO189
E	GLY190
E	MET192
E	THR194
E	PHE196
E	PHE197
E	HOH401
E	HOH404
E	HOH414
E	HOH433
E	HOH452
E	HOH462
E	HOH482
E	HOH486
E	HOH532
E	HOH547
E	HOH594

site_id	AC8
Number of Residues	34
Details	binding site for residue NAP F 300

Chain	Residue
F	GLY15
F	LYS18
F	ASN19
F	LEU20
F	HIS39
F	ASN41
F	SER42
F	SER45
F	ASP69
F	LEU70
F	THR71
F	THR96
F	VAL97
F	GLY98
F	VAL145
F	TYR159
F	LYS163
F	PRO189
F	GLY190
F	PRO191
F	MET192
F	THR194
F	PHE196
F	PHE197
F	HOH403
F	HOH405
F	HOH430
F	HOH434
F	HOH462
F	HOH466
F	HOH498
F	HOH553
F	HOH574
F	HOH584

site_id	AC9
Number of Residues	35
Details	binding site for residue NAP G 301

Chain	Residue
G	GLY15
G	LYS18
G	ASN19
G	LEU20
G	HIS39
G	ASN41
G	SER42
G	SER45
G	ALA68
G	ASP69
G	LEU70
G	THR71
G	THR96
G	VAL97
G	GLY98
G	VAL145
G	TYR159
G	LYS163
G	PRO189
G	GLY190
G	MET192
G	THR194
G	PHE196
G	PHE197
G	HOH402
G	HOH405
G	HOH433
G	HOH447
G	HOH467
G	HOH470
G	HOH471
G	HOH527
G	HOH575
G	HOH587
G	HOH605

site_id	AD1
Number of Residues	3
Details	binding site for residue MG G 302

Chain	Residue
G	LYS18
G	ASN19
G	HOH470

site_id	AD2
Number of Residues	35
Details	binding site for residue NAP H 301

Chain	Residue
H	GLY15
H	LYS18
H	ASN19
H	LEU20
H	HIS39
H	ASN41
H	SER42
H	SER45
H	ALA68
H	ASP69
H	LEU70
H	THR71
H	THR96
H	VAL97
H	GLY98
H	VAL145
H	TYR159
H	LYS163
H	PRO189
H	GLY190
H	MET192
H	THR194
H	PHE196
H	PHE197
H	HOH402
H	HOH407
H	HOH408
H	HOH429
H	HOH441
H	HOH445
H	HOH469
H	HOH517
H	HOH539
H	HOH546
H	HOH560

site_id	AD3
Number of Residues	11
Details	binding site for residue 1PE H 302

Chain	Residue
A	TYR208
A	TYR254
A	THR255
A	HOH568
H	THR153
H	TYR208
H	TYR254
H	THR255
H	HOH413
H	HOH446
H	HOH581

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)