5TF4
Crystal structure of enoyl-(acyl carrier protein) reductase from Bartonella henselae in complext with NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0006631 | biological_process | fatty acid metabolic process |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0006631 | biological_process | fatty acid metabolic process |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| E | 0006629 | biological_process | lipid metabolic process |
| E | 0006631 | biological_process | fatty acid metabolic process |
| E | 0006633 | biological_process | fatty acid biosynthetic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
| F | 0006629 | biological_process | lipid metabolic process |
| F | 0006631 | biological_process | fatty acid metabolic process |
| F | 0006633 | biological_process | fatty acid biosynthetic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | binding site for residue NAD A 300 |
| Chain | Residue |
| A | GLY17 |
| A | VAL69 |
| A | ALA95 |
| A | ILE96 |
| A | GLY97 |
| A | ILE122 |
| A | LEU147 |
| A | THR148 |
| A | LYS166 |
| A | ALA192 |
| A | PRO194 |
| A | LEU18 |
| A | ILE195 |
| A | THR197 |
| A | LEU198 |
| A | ALA199 |
| A | ALA200 |
| A | GOL301 |
| A | HOH421 |
| A | HOH432 |
| A | HOH442 |
| A | HOH459 |
| A | ALA19 |
| A | HOH469 |
| A | SER23 |
| A | ILE24 |
| A | GLN44 |
| A | MET48 |
| A | CYS67 |
| A | ASP68 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | TYR159 |
| A | ALA200 |
| A | ILE203 |
| A | PHE206 |
| A | NAD300 |
| site_id | AC3 |
| Number of Residues | 32 |
| Details | binding site for residue NAD B 300 |
| Chain | Residue |
| B | GLY17 |
| B | LEU18 |
| B | ALA19 |
| B | SER23 |
| B | ILE24 |
| B | GLN44 |
| B | MET48 |
| B | CYS67 |
| B | ASP68 |
| B | VAL69 |
| B | ALA95 |
| B | ILE96 |
| B | GLY97 |
| B | ILE122 |
| B | LEU147 |
| B | THR148 |
| B | TYR149 |
| B | MET162 |
| B | LYS166 |
| B | PRO194 |
| B | ILE195 |
| B | THR197 |
| B | LEU198 |
| B | ALA199 |
| B | ALA200 |
| B | GOL301 |
| B | HOH431 |
| B | HOH439 |
| B | HOH451 |
| B | HOH453 |
| B | HOH475 |
| B | HOH501 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| B | TYR159 |
| B | ALA200 |
| B | ILE203 |
| B | PHE206 |
| B | NAD300 |
| site_id | AC5 |
| Number of Residues | 30 |
| Details | binding site for residue NAD C 300 |
| Chain | Residue |
| C | HOH445 |
| C | HOH447 |
| C | HOH503 |
| C | GLY17 |
| C | LEU18 |
| C | ALA19 |
| C | SER23 |
| C | ILE24 |
| C | GLN44 |
| C | MET48 |
| C | CYS67 |
| C | ASP68 |
| C | VAL69 |
| C | ALA95 |
| C | ILE96 |
| C | GLY97 |
| C | ILE122 |
| C | LEU147 |
| C | THR148 |
| C | LYS166 |
| C | ALA192 |
| C | GLY193 |
| C | PRO194 |
| C | ILE195 |
| C | THR197 |
| C | LEU198 |
| C | ALA199 |
| C | ALA200 |
| C | GOL301 |
| C | HOH402 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | TYR159 |
| C | ALA200 |
| C | ILE203 |
| C | PHE206 |
| C | NAD300 |
| site_id | AC7 |
| Number of Residues | 30 |
| Details | binding site for residue NAD D 300 |
| Chain | Residue |
| D | GLY17 |
| D | LEU18 |
| D | ALA19 |
| D | SER23 |
| D | ILE24 |
| D | GLN44 |
| D | MET48 |
| D | CYS67 |
| D | ASP68 |
| D | VAL69 |
| D | ALA95 |
| D | ILE96 |
| D | GLY97 |
| D | ILE122 |
| D | LEU147 |
| D | THR148 |
| D | LYS166 |
| D | ALA192 |
| D | PRO194 |
| D | ILE195 |
| D | THR197 |
| D | LEU198 |
| D | ALA199 |
| D | ALA200 |
| D | GOL301 |
| D | HOH414 |
| D | HOH430 |
| D | HOH438 |
| D | HOH484 |
| D | HOH488 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | TYR159 |
| D | ALA200 |
| D | ILE203 |
| D | PHE206 |
| D | NAD300 |
| site_id | AC9 |
| Number of Residues | 28 |
| Details | binding site for residue NAD E 300 |
| Chain | Residue |
| E | GLY17 |
| E | ALA19 |
| E | SER23 |
| E | ILE24 |
| E | GLN44 |
| E | MET48 |
| E | CYS67 |
| E | ASP68 |
| E | VAL69 |
| E | ALA95 |
| E | ILE96 |
| E | GLY97 |
| E | ILE122 |
| E | LEU147 |
| E | THR148 |
| E | TYR149 |
| E | LYS166 |
| E | ALA192 |
| E | PRO194 |
| E | ILE195 |
| E | THR197 |
| E | ALA199 |
| E | PHE206 |
| E | HOH410 |
| E | HOH416 |
| E | HOH431 |
| E | HOH454 |
| E | HOH485 |
| site_id | AD1 |
| Number of Residues | 30 |
| Details | binding site for residue NAD F 300 |
| Chain | Residue |
| F | GLY17 |
| F | LEU18 |
| F | ALA19 |
| F | SER23 |
| F | ILE24 |
| F | GLN44 |
| F | CYS67 |
| F | ASP68 |
| F | VAL69 |
| F | ALA95 |
| F | ILE96 |
| F | GLY97 |
| F | ILE122 |
| F | LEU147 |
| F | THR148 |
| F | TYR149 |
| F | LYS166 |
| F | ALA192 |
| F | PRO194 |
| F | ILE195 |
| F | THR197 |
| F | LEU198 |
| F | ALA199 |
| F | ALA200 |
| F | GOL301 |
| F | HOH407 |
| F | HOH427 |
| F | HOH430 |
| F | HOH445 |
| F | HOH477 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 301 |
| Chain | Residue |
| F | TYR159 |
| F | ALA200 |
| F | ILE203 |
| F | NAD300 |
