5TDT
Oxygenated toluene intermediate in toluene 4-monooxygenase (T4moHD) after reaction in the crystal
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| A | 0042203 | biological_process | toluene catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| B | 0042203 | biological_process | toluene catabolic process |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| C | 0042203 | biological_process | toluene catabolic process |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| D | 0042203 | biological_process | toluene catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0042203 | biological_process | toluene catabolic process |
| F | 0004497 | molecular_function | monooxygenase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| F | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| F | 0042203 | biological_process | toluene catabolic process |
| G | 0004497 | molecular_function | monooxygenase activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0018638 | molecular_function | toluene 4-monooxygenase activity |
| G | 0042203 | biological_process | toluene catabolic process |
| H | 0004497 | molecular_function | monooxygenase activity |
| H | 0042203 | biological_process | toluene catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MBN A 503 |
| Chain | Residue |
| A | TYR331 |
| A | GLY334 |
| A | VAL335 |
| A | TRP338 |
| A | PRO403 |
| C | PHE14 |
| C | LEU15 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MBN A 504 |
| Chain | Residue |
| A | PRO403 |
| A | MET471 |
| A | TRP167 |
| A | PRO394 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue FE A 505 |
| Chain | Residue |
| A | GLU104 |
| A | GLU134 |
| A | HIS137 |
| A | PER501 |
| A | FE506 |
| A | HOH632 |
| A | HOH674 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue FE A 506 |
| Chain | Residue |
| A | GLU134 |
| A | GLU197 |
| A | GLU231 |
| A | HIS234 |
| A | PER501 |
| A | FE505 |
| A | HOH632 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue MBN D 501 |
| Chain | Residue |
| D | TRP167 |
| D | TRP338 |
| D | THR341 |
| D | LEU393 |
| D | PRO394 |
| D | MET471 |
| D | MBN502 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue MBN D 502 |
| Chain | Residue |
| D | TYR331 |
| D | GLY334 |
| D | VAL335 |
| D | TRP338 |
| D | PRO394 |
| D | PRO403 |
| D | MBN501 |
| G | PHE14 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue FE D 503 |
| Chain | Residue |
| D | GLU104 |
| D | GLU134 |
| D | HIS137 |
| D | FE504 |
| D | HOH638 |
| D | HOH794 |
| D | HOH957 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue FE D 504 |
| Chain | Residue |
| D | GLU134 |
| D | GLU197 |
| D | GLU231 |
| D | HIS234 |
| D | FE503 |
| D | HOH638 |
| D | HOH957 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residues PER A 501 and MBN A 502 |
| Chain | Residue |
| A | ILE100 |
| A | GLY103 |
| A | GLU104 |
| A | ALA107 |
| A | GLU134 |
| A | PHE176 |
| A | GLU197 |
| A | GLU231 |
| A | FE505 |
| A | FE506 |
| A | HOH632 |
| A | HOH674 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19033467","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19290655","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19705873","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22264099","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25248368","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28346937","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3Q14","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q2A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3Q3O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RI7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3RMK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4P1C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDV","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
