5TDC
Crystal structure of the human UBR-box domain from UBR1 in complex with monomethylated arginine peptide.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| A | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0061630 | molecular_function | ubiquitin protein ligase activity |
| C | 0071596 | biological_process | ubiquitin-dependent protein catabolic process via the N-end rule pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 201 |
| Chain | Residue |
| A | CYS99 |
| A | CYS124 |
| A | CYS127 |
| A | CYS149 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 202 |
| Chain | Residue |
| A | CYS127 |
| A | CYS151 |
| A | CYS163 |
| A | HIS166 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 203 |
| Chain | Residue |
| A | CYS115 |
| A | HIS133 |
| A | HIS136 |
| A | CYS112 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | PHE103 |
| A | HIS141 |
| A | SER143 |
| A | THR144 |
| A | GLY145 |
| A | GLY146 |
| A | GLY147 |
| A | HOH309 |
| A | HOH310 |
| A | HOH312 |
| B | ILE2 |
| B | PHE3 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 201 |
| Chain | Residue |
| C | CYS99 |
| C | CYS124 |
| C | CYS127 |
| C | CYS149 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 202 |
| Chain | Residue |
| C | CYS127 |
| C | CYS151 |
| C | CYS163 |
| C | HIS166 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 203 |
| Chain | Residue |
| C | CYS112 |
| C | CYS115 |
| C | HIS133 |
| C | HIS136 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | binding site for residue SO4 C 204 |
| Chain | Residue |
| C | PHE103 |
| C | HIS141 |
| C | SER143 |
| C | THR144 |
| C | GLY145 |
| C | GLY146 |
| C | GLY147 |
| C | HOH302 |
| C | HOH305 |
| C | HOH312 |
| D | ILE2 |
| D | PHE3 |
| site_id | AC9 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide NMM B 1 and ILE B 2 |
| Chain | Residue |
| A | THR120 |
| A | CYS121 |
| A | HIS141 |
| A | GLY147 |
| A | PHE148 |
| A | ASP150 |
| A | ASP153 |
| A | GLU155 |
| A | SO4204 |
| A | HOH301 |
| B | PHE3 |
| B | HOH101 |
| B | HOH102 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide NMM D 1 and ILE D 2 |
| Chain | Residue |
| C | THR120 |
| C | HIS141 |
| C | GLY147 |
| C | PHE148 |
| C | ASP150 |
| C | ASP153 |
| C | SO4204 |
| C | HOH301 |
| D | PHE3 |
| D | HOH102 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P19812","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20835242","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28392261","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3NY1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5TDC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8IWV8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
