Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003938 | molecular_function | IMP dehydrogenase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006177 | biological_process | GMP biosynthetic process |
| A | 0006183 | biological_process | GTP biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003938 | molecular_function | IMP dehydrogenase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006177 | biological_process | GMP biosynthetic process |
| B | 0006183 | biological_process | GTP biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 5GP A 600 |
| Chain | Residue |
| A | SER74 |
| A | GLN371 |
| A | MET388 |
| A | GLY390 |
| A | GLY391 |
| A | TYR414 |
| A | GLY418 |
| A | GLN448 |
| A | ASN306 |
| A | ARG325 |
| A | GLY331 |
| A | SER332 |
| A | CYS334 |
| A | THR336 |
| A | ASP367 |
| A | GLY369 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue ATP A 601 |
| Chain | Residue |
| A | THR165 |
| A | ARG167 |
| A | ASP168 |
| A | THR184 |
| A | ASP186 |
| A | VAL187 |
| A | ILE188 |
| A | LYS208 |
| A | GLY209 |
| A | LYS210 |
| A | GDP602 |
| A | HOH707 |
| A | HOH708 |
| B | ARG167 |
| B | LYS207 |
| B | ATP601 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue GDP A 602 |
| Chain | Residue |
| A | LYS115 |
| A | TYR116 |
| A | ASN118 |
| A | PRO124 |
| A | VAL125 |
| A | PHE145 |
| A | ALA146 |
| A | GLY147 |
| A | LYS210 |
| A | MET223 |
| A | SER225 |
| A | THR227 |
| A | ASP228 |
| A | LYS231 |
| A | ATP601 |
| A | HOH707 |
| A | HOH708 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue GDP A 603 |
| Chain | Residue |
| A | GLU117 |
| A | ASN118 |
| A | GLY119 |
| A | ASN200 |
| A | ASP228 |
| A | LEU229 |
| A | ASN232 |
| A | PRO236 |
| A | LYS240 |
| A | LYS245 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 604 |
| Chain | Residue |
| B | ARG260 |
| B | HOH723 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | binding site for residue 5GP B 600 |
| Chain | Residue |
| B | SER74 |
| B | ASN306 |
| B | ARG325 |
| B | GLY331 |
| B | SER332 |
| B | CYS334 |
| B | THR336 |
| B | ASP367 |
| B | GLY369 |
| B | GLN371 |
| B | MET388 |
| B | GLY390 |
| B | GLY391 |
| B | TYR414 |
| B | GLY418 |
| B | SER419 |
| B | GLN448 |
| B | HOH701 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue ATP B 601 |
| Chain | Residue |
| A | ARG167 |
| A | LYS207 |
| A | ATP601 |
| B | ILE163 |
| B | THR165 |
| B | ARG167 |
| B | ASP168 |
| B | THR184 |
| B | ASP186 |
| B | VAL187 |
| B | ILE188 |
| B | LYS208 |
| B | GLY209 |
| B | LYS210 |
| B | GDP602 |
| B | HOH702 |
| B | HOH706 |
| B | HOH707 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | binding site for residue GDP B 602 |
| Chain | Residue |
| B | ASN118 |
| B | ILE121 |
| B | PRO124 |
| B | VAL125 |
| B | PHE145 |
| B | ALA146 |
| B | GLY147 |
| B | LYS210 |
| B | MET223 |
| B | SER225 |
| B | THR227 |
| B | ASP228 |
| B | LYS231 |
| B | ATP601 |
| B | HOH702 |
| B | LYS115 |
| B | TYR116 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | binding site for residue GDP B 603 |
| Chain | Residue |
| B | GLU117 |
| B | ASN118 |
| B | GLY119 |
| B | LEU196 |
| B | ASN200 |
| B | ASP228 |
| B | LEU229 |
| B | ASN232 |
| B | TYR235 |
| B | PRO236 |
| B | LYS240 |
| B | LYS245 |
Functional Information from PROSITE/UniProt
| site_id | PS00487 |
| Number of Residues | 13 |
| Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. LRIGMGsGSICiT |
| Chain | Residue | Details |
| A | LEU324-THR336 | |
