5TBV
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with tubercidin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue TBN A 301 |
| Chain | Residue |
| A | HIS88 |
| A | HIS259 |
| A | VAL262 |
| A | SO4302 |
| A | HOH407 |
| A | TYR90 |
| A | LEU118 |
| A | GLY120 |
| A | TYR202 |
| A | GLU203 |
| A | GLY220 |
| A | MET221 |
| A | ASN245 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | GLY34 |
| A | SER35 |
| A | HIS66 |
| A | ARG86 |
| A | HIS88 |
| A | ASN117 |
| A | LEU118 |
| A | SER222 |
| A | TBN301 |
| A | HOH430 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 303 |
| Chain | Residue |
| A | ASN95 |
| A | GLN96 |
| A | ALA99 |
| A | ARG103 |
| A | VAL148 |
| A | VAL150 |
| A | HOH436 |
