5TBU
Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with Hypoxanthine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
A | 0009116 | biological_process | nucleoside metabolic process |
A | 0016757 | molecular_function | glycosyltransferase activity |
A | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue HPA A 301 |
Chain | Residue |
A | ALA119 |
A | HOH491 |
A | GLY120 |
A | TYR202 |
A | GLU203 |
A | VAL219 |
A | ASN245 |
A | SER247 |
A | VAL262 |
A | HOH402 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue DMS A 302 |
Chain | Residue |
A | ASP163 |
A | CYS231 |
A | HIS232 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue DMS A 303 |
Chain | Residue |
A | ASN95 |
A | ALA99 |
A | ARG103 |
A | VAL148 |
A | LEU149 |
A | VAL150 |
A | HOH423 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue DMS A 304 |
Chain | Residue |
A | LEU118 |
A | PHE161 |
A | TYR202 |
A | MET221 |
A | HIS259 |
A | VAL262 |