5T9G
Crystal structure of BuGH2Cwt in complex with Galactoisofagomine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue GIF A 901 |
| Chain | Residue |
| A | ARG166 |
| A | HIS355 |
| A | ASN390 |
| A | GLU436 |
| A | GLU552 |
| A | TRP575 |
| A | GLU583 |
| A | HOH1091 |
| A | HOH1099 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 902 |
| Chain | Residue |
| B | TRP410 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 903 |
| Chain | Residue |
| A | VAL335 |
| A | ARG338 |
| A | ARG339 |
| A | ALA604 |
| A | GLY605 |
| A | HIS760 |
| A | HOH1035 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 904 |
| Chain | Residue |
| A | ASP111 |
| A | GLN178 |
| A | TRP190 |
| A | ASP360 |
| A | ARG421 |
| A | HOH1011 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GIF B 901 |
| Chain | Residue |
| B | ARG166 |
| B | HIS355 |
| B | ASN390 |
| B | GLU436 |
| B | GLU552 |
| B | TRP575 |
| B | GLU583 |
| B | HOH1030 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 902 |
| Chain | Residue |
| B | VAL194 |
| B | GLY294 |
| B | ARG423 |
| B | ASN424 |
| B | PRO426 |
| B | ARG503 |
| B | HOH1014 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 903 |
| Chain | Residue |
| B | GLN556 |
| B | TRP557 |
| B | HIS558 |
| B | TRP652 |
| B | ARG655 |
| B | ASP704 |
| B | ILE706 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 904 |
| Chain | Residue |
| B | GLU78 |
| B | GLY79 |
| B | CYS80 |
| B | ARG388 |
| B | VAL584 |
| B | GLY585 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 905 |
| Chain | Residue |
| B | PRO197 |
| B | THR502 |
| B | HOH1175 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 906 |
| Chain | Residue |
| B | PRO504 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for residue GIF C 901 |
| Chain | Residue |
| C | ARG166 |
| C | HIS355 |
| C | ASN390 |
| C | GLU436 |
| C | GLU552 |
| C | TRP575 |
| C | GLU583 |
| C | EDO906 |
| C | HOH1026 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 902 |
| Chain | Residue |
| C | GLN408 |
| C | LYS491 |
| C | TRP495 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 903 |
| Chain | Residue |
| C | HIS321 |
| C | HIS322 |
| C | LEU331 |
| C | LEU353 |
| C | ALA359 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 904 |
| Chain | Residue |
| C | PHE136 |
| C | PHE137 |
| C | ASN417 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 905 |
| Chain | Residue |
| C | PHE460 |
| C | TRP461 |
| C | TYR531 |
| C | ARG533 |
| C | GLU559 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 906 |
| Chain | Residue |
| C | ARG589 |
| C | TRP657 |
| C | GIF901 |
| C | HOH1173 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue GIF D 901 |
| Chain | Residue |
| D | ARG166 |
| D | HIS355 |
| D | ASN390 |
| D | GLU436 |
| D | GLU552 |
| D | TRP575 |
| D | GLU583 |
| D | EDO902 |
| D | HOH1054 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 902 |
| Chain | Residue |
| D | ARG589 |
| D | ILE596 |
| D | TRP657 |
| D | GIF901 |
