5T94

Crystal structure of Kap60 bound to yeast RCC1 (Prp20)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000054	biological_process	ribosomal subunit export from nucleus
A	0000785	cellular_component	chromatin
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0006606	biological_process	protein import into nucleus
A	0006997	biological_process	nucleus organization
A	0007346	biological_process	regulation of mitotic cell cycle
A	0016973	biological_process	poly(A)+ mRNA export from nucleus
A	0019236	biological_process	response to pheromone
A	0051301	biological_process	cell division
A	1901673	biological_process	regulation of mitotic spindle assembly
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006606	biological_process	protein import into nucleus
B	0006607	biological_process	NLS-bearing protein import into nucleus
B	0006612	biological_process	protein targeting to membrane
B	0008139	molecular_function	nuclear localization sequence binding
B	0015031	biological_process	protein transport
B	0031144	biological_process	proteasome localization
B	0032991	cellular_component	protein-containing complex
B	0042564	cellular_component	NLS-dependent protein nuclear import complex
B	0044877	molecular_function	protein-containing complex binding
B	0048471	cellular_component	perinuclear region of cytoplasm
B	0051170	biological_process	import into nucleus
B	0061608	molecular_function	nuclear import signal receptor activity
B	0097718	molecular_function	disordered domain specific binding

Functional Information from PROSITE/UniProt

site_id	PS00625
Number of Residues	12
Details	RCC1_1 Regulator of chromosome condensation (RCC1) signature 1. GcNDvgALGRdT

Chain	Residue	Details
A	GLY109-THR120

---

site_id	PS00626
Number of Residues	11
Details	RCC1_2 Regulator of chromosome condensation (RCC1) signature 2. VAAGsHHSVAV

Chain	Residue	Details
A	VAL399-VAL409

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Repeat: {"description":"RCC1 1"}

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site_id	SWS_FT_FI2
Number of Residues	55
Details	Repeat: {"description":"RCC1 3"}

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site_id	SWS_FT_FI3
Number of Residues	52
Details	Repeat: {"description":"RCC1 4"}

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site_id	SWS_FT_FI4
Number of Residues	55
Details	Repeat: {"description":"RCC1 5"}

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site_id	SWS_FT_FI5
Number of Residues	62
Details	Repeat: {"description":"RCC1 6"}

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site_id	SWS_FT_FI6
Number of Residues	54
Details	Repeat: {"description":"RCC1 7"}

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Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	33
Details	Repeat: {"description":"ARM 1; truncated","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	39
Details	Repeat: {"description":"ARM 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI9
Number of Residues	41
Details	Repeat: {"description":"ARM 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI10
Number of Residues	46
Details	Repeat: {"description":"ARM 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI11
Number of Residues	36
Details	Repeat: {"description":"ARM 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	41
Details	Repeat: {"description":"ARM 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	41
Details	Repeat: {"description":"ARM 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI14
Number of Residues	44
Details	Repeat: {"description":"ARM 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

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Residue

Details

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site_id	SWS_FT_FI15
Number of Residues	53
Details	Repeat: {"description":"ARM 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI16
Number of Residues	36
Details	Repeat: {"description":"ARM 10; atypical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00259","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8521485","evidenceCode":"ECO:0000269"}]}

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Residue

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site_id	SWS_FT_FI17
Number of Residues	126
Details	Region: {"description":"NLS binding site 1"}

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site_id	SWS_FT_FI18
Number of Residues	86
Details	Region: {"description":"NLS binding site 2"}

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