Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0005789 | cellular_component | endoplasmic reticulum membrane |
A | 0016020 | cellular_component | membrane |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0016712 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 23 |
Details | binding site for residue HEM A 600 |
Chain | Residue |
A | LYS105 |
A | VAL375 |
A | VAL378 |
A | PRO440 |
A | PHE441 |
A | ARG446 |
A | ASN447 |
A | CYS448 |
A | GLY450 |
A | PHE453 |
A | ALA454 |
A | TYR110 |
A | MET458 |
A | OCT601 |
A | HOH705 |
A | HOH708 |
A | LEU121 |
A | TRP129 |
A | ARG133 |
A | PHE140 |
A | GLU310 |
A | GLY311 |
A | PRO374 |
site_id | AC2 |
Number of Residues | 2 |
Details | binding site for residue OCT A 601 |
Chain | Residue |
A | THR314 |
A | HEM600 |
Functional Information from PROSITE/UniProt
site_id | PS00086 |
Number of Residues | 10 |
Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FSaGPRNCIG |
Chain | Residue | Details |
A | PHE441-GLY450 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | GLU310 | |
Chain | Residue | Details |
A | CYS448 | |
Chain | Residue | Details |
A | SER431 | |