5T6M

Structure of the tryptophan synthase b-subunit from Pyroccus furiosus with b-methyltryptophan non-covalently bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000162	biological_process	tryptophan biosynthetic process
A	0004834	molecular_function	tryptophan synthase activity
A	0005737	cellular_component	cytoplasm
A	0006568	biological_process	tryptophan metabolic process
A	0016829	molecular_function	lyase activity
B	0000162	biological_process	tryptophan biosynthetic process
B	0004834	molecular_function	tryptophan synthase activity
B	0005737	cellular_component	cytoplasm
B	0006568	biological_process	tryptophan metabolic process
B	0016829	molecular_function	lyase activity
C	0000162	biological_process	tryptophan biosynthetic process
C	0004834	molecular_function	tryptophan synthase activity
C	0005737	cellular_component	cytoplasm
C	0006568	biological_process	tryptophan metabolic process
C	0016829	molecular_function	lyase activity
D	0000162	biological_process	tryptophan biosynthetic process
D	0004834	molecular_function	tryptophan synthase activity
D	0005737	cellular_component	cytoplasm
D	0006568	biological_process	tryptophan metabolic process
D	0016829	molecular_function	lyase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue NA A 401

Chain	Residue
A	SER263
A	SER265
A	TYR301
A	GLY303
A	HOH548
A	HOH551

---

site_id	AC2
Number of Residues	8
Details	binding site for residue PO4 A 402

Chain	Residue
A	ALA107
A	GLY108
A	GLN109
A	HIS110
A	HOH502
A	LLP82
A	THR105
A	GLY106

---

site_id	AC3
Number of Residues	7
Details	binding site for residue NA B 401

Chain	Residue
B	GLY227
B	SER263
B	SER265
B	TYR301
B	GLY303
B	HOH519
B	HOH549

---

site_id	AC4
Number of Residues	12
Details	binding site for residue 78U B 402

Chain	Residue
B	LLP82
B	GLU104
B	THR105
B	GLY106
B	ALA107
B	GLY108
B	GLN109
B	HIS110
B	LEU161
B	GLY298
B	TYR301
B	HOH523

---

site_id	AC5
Number of Residues	7
Details	binding site for residue NA C 401

Chain	Residue
C	GLY227
C	SER263
C	SER265
C	TYR301
C	GLY303
C	HOH524
C	HOH538

---

site_id	AC6
Number of Residues	12
Details	binding site for residue 78U C 402

Chain	Residue
C	LLP82
C	GLU104
C	THR105
C	GLY106
C	ALA107
C	GLN109
C	HIS110
C	LEU161
C	VAL187
C	GLY298
C	TYR301
C	HOH508

---

site_id	AC7
Number of Residues	6
Details	binding site for residue NA D 401

Chain	Residue
D	GLY227
D	SER263
D	SER265
D	TYR301
D	GLY303
D	HOH536

---

site_id	AC8
Number of Residues	6
Details	binding site for residue PO4 D 402

Chain	Residue
D	THR105
D	GLY106
D	ALA107
D	GLN109
D	HIS110
D	HOH548

---

site_id	AC9
Number of Residues	9
Details	binding site for residue 78U D 403

Chain	Residue
D	GLU104
D	LEU169
D	TYR181
D	ILE183
D	PRO189
D	HIS275
D	TYR301
D	HOH525
D	HOH542

---

Functional Information from PROSITE/UniProt

site_id	PS00168
Number of Residues	15
Details	TRP_SYNTHASE_BETA Tryptophan synthase beta chain pyridoxal-phosphate attachment site. LvHgGAHKtNnaIgQ

Chain	Residue	Details
A	LEU75-GLN89

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000250

Chain	Residue	Details
A	LLP82
B	LLP82
C	LLP82
D	LLP82

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