Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

5T61

TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, TRICLINIC FORM AT 2.55 A

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0015948	biological_process	methanogenesis
B	0016491	molecular_function	oxidoreductase activity
B	0018493	molecular_function	formylmethanofuran dehydrogenase activity
C	0015948	biological_process	methanogenesis
C	0016491	molecular_function	oxidoreductase activity
C	0018493	molecular_function	formylmethanofuran dehydrogenase activity
C	0046914	molecular_function	transition metal ion binding
D	0016491	molecular_function	oxidoreductase activity
D	0043546	molecular_function	molybdopterin cofactor binding
G	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
H	0015948	biological_process	methanogenesis
H	0016491	molecular_function	oxidoreductase activity
H	0018493	molecular_function	formylmethanofuran dehydrogenase activity
I	0015948	biological_process	methanogenesis
I	0016491	molecular_function	oxidoreductase activity
I	0018493	molecular_function	formylmethanofuran dehydrogenase activity
I	0046914	molecular_function	transition metal ion binding
J	0016491	molecular_function	oxidoreductase activity
J	0043546	molecular_function	molybdopterin cofactor binding
M	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
N	0015948	biological_process	methanogenesis
N	0016491	molecular_function	oxidoreductase activity
N	0018493	molecular_function	formylmethanofuran dehydrogenase activity
O	0015948	biological_process	methanogenesis
O	0016491	molecular_function	oxidoreductase activity
O	0018493	molecular_function	formylmethanofuran dehydrogenase activity
O	0046914	molecular_function	transition metal ion binding
P	0016491	molecular_function	oxidoreductase activity
P	0043546	molecular_function	molybdopterin cofactor binding
S	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
T	0015948	biological_process	methanogenesis
T	0016491	molecular_function	oxidoreductase activity
T	0018493	molecular_function	formylmethanofuran dehydrogenase activity
U	0015948	biological_process	methanogenesis
U	0016491	molecular_function	oxidoreductase activity
U	0018493	molecular_function	formylmethanofuran dehydrogenase activity
U	0046914	molecular_function	transition metal ion binding
V	0016491	molecular_function	oxidoreductase activity
V	0043546	molecular_function	molybdopterin cofactor binding
Y	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Z	0015948	biological_process	methanogenesis
Z	0016491	molecular_function	oxidoreductase activity
Z	0018493	molecular_function	formylmethanofuran dehydrogenase activity
a	0015948	biological_process	methanogenesis
a	0016491	molecular_function	oxidoreductase activity
a	0018493	molecular_function	formylmethanofuran dehydrogenase activity
a	0046914	molecular_function	transition metal ion binding
b	0016491	molecular_function	oxidoreductase activity
b	0043546	molecular_function	molybdopterin cofactor binding
e	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
f	0015948	biological_process	methanogenesis
f	0016491	molecular_function	oxidoreductase activity
f	0018493	molecular_function	formylmethanofuran dehydrogenase activity
g	0015948	biological_process	methanogenesis
g	0016491	molecular_function	oxidoreductase activity
g	0018493	molecular_function	formylmethanofuran dehydrogenase activity
g	0046914	molecular_function	transition metal ion binding
h	0016491	molecular_function	oxidoreductase activity
h	0043546	molecular_function	molybdopterin cofactor binding
k	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
l	0015948	biological_process	methanogenesis
l	0016491	molecular_function	oxidoreductase activity
l	0018493	molecular_function	formylmethanofuran dehydrogenase activity
m	0015948	biological_process	methanogenesis
m	0016491	molecular_function	oxidoreductase activity
m	0018493	molecular_function	formylmethanofuran dehydrogenase activity
m	0046914	molecular_function	transition metal ion binding
n	0016491	molecular_function	oxidoreductase activity
n	0043546	molecular_function	molybdopterin cofactor binding
q	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
r	0015948	biological_process	methanogenesis
r	0016491	molecular_function	oxidoreductase activity
r	0018493	molecular_function	formylmethanofuran dehydrogenase activity
s	0015948	biological_process	methanogenesis
s	0016491	molecular_function	oxidoreductase activity
s	0018493	molecular_function	formylmethanofuran dehydrogenase activity
s	0046914	molecular_function	transition metal ion binding
t	0016491	molecular_function	oxidoreductase activity
t	0043546	molecular_function	molybdopterin cofactor binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 601

Chain	Residue
A	KCX178
A	HIS231
A	HIS271
A	ZN602
A	MFN603

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 602

Chain	Residue
A	ZN601
A	HIS57
A	HIS59
A	KCX178
A	ASP385

site_id	AC3
Number of Residues	20
Details	binding site for residue MFN A 603

Chain	Residue
A	HIS231
A	LEU235
A	HIS271
A	PHE274
A	TRP282
A	ARG283
A	THR318
A	MET323
A	GLU324
A	PHE351
A	TYR353
A	PRO358
A	VAL359
A	GLN363
A	ASP385
A	ASN388
A	LYS418
A	TRP419
A	ARG422
A	ZN601

site_id	AC4
Number of Residues	4
Details	binding site for residue NA A 604

Chain	Residue
A	GLY144
A	ASN145
A	VAL180
A	HOH708

site_id	AC5
Number of Residues	5
Details	binding site for residue K A 605

Chain	Residue
A	VAL340
A	THR344
A	HOH714
A	HOH715
B	GLU138

site_id	AC6
Number of Residues	4
Details	binding site for residue SF4 B 501

Chain	Residue
B	CYS9
B	CYS12
B	CYS16
B	CYS35

site_id	AC7
Number of Residues	4
Details	binding site for residue W B 502

Chain	Residue
B	CYS118
B	MGD503
B	MGD504
B	H2S505

site_id	AC8
Number of Residues	29
Details	binding site for residue MGD B 503

Chain	Residue
B	LYS41
B	CYS91
B	THR114
B	VAL117
B	CYS118
B	HIS258
B	HIS290
B	ALA342
B	SER343
B	ASP344
B	HIS348
B	ILE365
B	GLU366
B	PRO367
B	HIS368
B	PRO382
B	ILE384
B	VAL385
B	ASP414
B	W502
B	MGD504
B	H2S505
D	THR7
D	ARG9
D	LYS21
D	MET80
D	ASN85
D	PHE100
D	LYS101

site_id	AC9
Number of Residues	34
Details	binding site for residue MGD B 504

Chain	Residue
B	H2S505
D	ASN6
D	GLY8
D	ARG9
D	THR10
D	GLN13
D	GLY14
D	ILE17
D	MET80
D	LYS101
D	ASN102
B	PHE11
B	ILE37
B	CYS118
B	GLY150
B	CYS151
B	ASN152
B	HIS155
B	ALA156
B	VAL184
B	ASP185
B	PRO186
B	ARG187
B	PHE203
B	ASP204
B	ASP206
B	GLY253
B	MET254
B	GLY255
B	SER259
B	GLY289
B	HIS290
B	W502
B	MGD503

site_id	AD1
Number of Residues	6
Details	binding site for residue H2S B 505

Chain	Residue
B	THR114
B	CYS118
B	HIS290
B	W502
B	MGD503
B	MGD504

site_id	AD2
Number of Residues	4
Details	binding site for residue K B 506

Chain	Residue
B	SER40
B	LYS41
B	VAL43
D	GLU18

site_id	AD3
Number of Residues	6
Details	binding site for residue MG B 507

Chain	Residue
B	ASP128
C	SER139
C	TYR140
C	ASP143
C	GLU164
C	TYR165

site_id	AD4
Number of Residues	6
Details	binding site for residue SF4 E 101

Chain	Residue
E	CYS12
E	CYS15
E	GLY16
E	CYS18
E	VAL53
E	CYS71

site_id	AD5
Number of Residues	5
Details	binding site for residue SF4 E 102

Chain	Residue
E	CYS22
E	CYS61
E	CYS64
E	GLY65
E	CYS67

site_id	AD6
Number of Residues	3
Details	binding site for residue K E 103

Chain	Residue
E	VAL68
E	CYS71
E	ASP74

site_id	AD7
Number of Residues	5
Details	binding site for residue SF4 F 401

Chain	Residue
F	CYS281
F	VAL285
F	CYS308
F	CYS311
F	CYS314

site_id	AD8
Number of Residues	7
Details	binding site for residue SF4 F 402

Chain	Residue
F	CYS271
F	GLN272
F	ALA273
F	CYS274
F	GLU275
F	CYS277
F	CYS318

site_id	AD9
Number of Residues	6
Details	binding site for residue SF4 F 403

Chain	Residue
F	CYS41
F	CYS71
F	LEU73
F	CYS74
F	GLY75
F	CYS77

site_id	AE1
Number of Residues	6
Details	binding site for residue SF4 F 404

Chain	Residue
F	CYS31
F	CYS34
F	GLY35
F	CYS37
F	CYS81
F	PHE83

site_id	AE2
Number of Residues	7
Details	binding site for residue SF4 F 405

Chain	Residue
F	CYS125
F	CYS239
F	VAL240
F	ASN241
F	CYS242
F	GLY243
F	CYS245

site_id	AE3
Number of Residues	5
Details	binding site for residue SF4 F 406

Chain	Residue
F	CYS115
F	CYS118
F	LYS119
F	CYS121
F	CYS249

site_id	AE4
Number of Residues	4
Details	binding site for residue SF4 F 407

Chain	Residue
F	CYS213
F	CYS216
L	CYS213
L	CYS216

site_id	AE5
Number of Residues	4
Details	binding site for residue SF4 F 408

Chain	Residue
F	CYS154
F	CYS157
F	CYS160
F	CYS204

site_id	AE6
Number of Residues	6
Details	binding site for residue SF4 F 409

Chain	Residue
F	CYS164
F	CYS194
F	HIS196
F	CYS197
F	GLY198
F	CYS200

site_id	AE7
Number of Residues	4
Details	binding site for residue K F 410

Chain	Residue
F	GLU161
F	GLU162
F	CYS164
F	ASP167

site_id	AE8
Number of Residues	4
Details	binding site for residue K F 411

Chain	Residue
F	GLU122
F	THR123
F	CYS125
F	ASP128

site_id	AE9
Number of Residues	4
Details	binding site for residue K F 412

Chain	Residue
F	GLN246
F	GLU247
F	CYS249
F	ASP252

site_id	AF1
Number of Residues	3
Details	binding site for residue K F 413

Chain	Residue
F	VAL195
F	HIS196
F	CYS213

site_id	AF2
Number of Residues	5
Details	binding site for residue ZN G 601

Chain	Residue
G	KCX178
G	HIS231
G	HIS271
G	ZN602
G	MFN603

site_id	AF3
Number of Residues	5
Details	binding site for residue ZN G 602

Chain	Residue
G	HIS57
G	HIS59
G	KCX178
G	ASP385
G	ZN601

site_id	AF4
Number of Residues	21
Details	binding site for residue MFN G 603

Chain	Residue
G	HIS231
G	LEU235
G	HIS271
G	PHE274
G	TRP282
G	ARG283
G	THR318
G	MET323
G	LEU330
G	PHE351
G	TYR353
G	PRO358
G	VAL359
G	GLN363
G	ASP385
G	ASN388
G	HIS417
G	LYS418
G	TRP419
G	ARG422
G	ZN601

site_id	AF5
Number of Residues	2
Details	binding site for residue NA G 604

Chain	Residue
G	ASN145
G	VAL180

site_id	AF6
Number of Residues	5
Details	binding site for residue K G 605

Chain	Residue
G	VAL340
G	THR344
G	HOH704
G	HOH708
H	GLU138

site_id	AF7
Number of Residues	4
Details	binding site for residue SF4 H 501

Chain	Residue
H	CYS9
H	CYS12
H	CYS16
H	CYS35

site_id	AF8
Number of Residues	4
Details	binding site for residue W H 502

Chain	Residue
H	CYS118
H	MGD503
H	MGD504
H	H2S505

site_id	AF9
Number of Residues	29
Details	binding site for residue MGD H 503

Chain	Residue
H	LYS41
H	CYS91
H	VAL117
H	CYS118
H	HIS290
H	ALA342
H	SER343
H	ASP344
H	HIS348
H	ILE365
H	GLU366
H	PRO367
H	HIS368
H	THR370
H	PRO382
H	ILE384
H	VAL385
H	ASP414
H	W502
H	MGD504
H	H2S505
J	THR7
J	GLY8
J	ARG9
J	LYS21
J	MET80
J	ASN85
J	PHE100
J	LYS101

site_id	AG1
Number of Residues	37
Details	binding site for residue MGD H 504

Chain	Residue
H	PHE11
H	ILE37
H	CYS118
H	GLY150
H	CYS151
H	ASN152
H	HIS155
H	ALA156
H	HIS157
H	VAL184
H	ASP185
H	PRO186
H	ARG187
H	THR189
H	PHE203
H	ASP204
H	ASP206
H	GLY253
H	MET254
H	GLY255
H	SER259
H	GLY289
H	HIS290
H	W502
H	MGD503
H	H2S505
H	HOH606
H	HOH609
J	ASN6
J	GLY8
J	ARG9
J	THR10
J	GLN13
J	GLY14
J	MET80
J	LYS101
J	ASN102

site_id	AG2
Number of Residues	5
Details	binding site for residue H2S H 505

Chain	Residue
H	CYS118
H	HIS290
H	W502
H	MGD503
H	MGD504

site_id	AG3
Number of Residues	6
Details	binding site for residue MG H 506

Chain	Residue
H	ASP128
I	SER139
I	TYR140
I	ASP143
I	GLU164
I	TYR165

site_id	AG4
Number of Residues	5
Details	binding site for residue SF4 K 101

Chain	Residue
K	CYS12
K	CYS15
K	GLY16
K	CYS18
K	CYS71

site_id	AG5
Number of Residues	5
Details	binding site for residue SF4 K 102

Chain	Residue
K	CYS22
K	CYS61
K	CYS64
K	GLY65
K	CYS67

site_id	AG6
Number of Residues	4
Details	binding site for residue K K 103

Chain	Residue
K	VAL68
K	CYS71
K	ASP74
K	HOH203

site_id	AG7
Number of Residues	5
Details	binding site for residue SF4 L 501

Chain	Residue
L	CYS154
L	CYS157
L	CYS160
L	CYS204
L	PRO205

site_id	AG8
Number of Residues	5
Details	binding site for residue SF4 L 502

Chain	Residue
L	CYS164
L	CYS194
L	CYS197
L	GLY198
L	CYS200

site_id	AG9
Number of Residues	6
Details	binding site for residue SF4 L 503

Chain	Residue
L	CYS281
L	VAL285
L	CYS308
L	CYS311
L	GLY312
L	CYS314

site_id	AH1
Number of Residues	7
Details	binding site for residue SF4 L 504

Chain	Residue
L	CYS271
L	GLN272
L	ALA273
L	CYS274
L	GLU275
L	CYS277
L	CYS318

site_id	AH2
Number of Residues	6
Details	binding site for residue SF4 L 505

Chain	Residue
L	CYS41
L	CYS71
L	LEU73
L	CYS74
L	GLY75
L	CYS77

site_id	AH3
Number of Residues	5
Details	binding site for residue SF4 L 506

Chain	Residue
L	CYS31
L	CYS34
L	GLY35
L	CYS37
L	CYS81

site_id	AH4
Number of Residues	7
Details	binding site for residue SF4 L 507

Chain	Residue
L	CYS125
L	CYS239
L	VAL240
L	ASN241
L	CYS242
L	GLY243
L	CYS245

site_id	AH5
Number of Residues	5
Details	binding site for residue SF4 L 508

Chain	Residue
L	CYS115
L	CYS118
L	LYS119
L	CYS121
L	CYS249

site_id	AH6
Number of Residues	4
Details	binding site for residue K L 509

Chain	Residue
L	GLU161
L	GLU162
L	CYS164
L	ASP167

site_id	AH7
Number of Residues	4
Details	binding site for residue K L 510

Chain	Residue
L	GLN246
L	GLU247
L	CYS249
L	ASP252

site_id	AH8
Number of Residues	3
Details	binding site for residue K L 511

Chain	Residue
L	GLU5
L	ILE66
L	GLU68

site_id	AH9
Number of Residues	5
Details	binding site for residue ZN M 601

Chain	Residue
M	KCX178
M	HIS231
M	HIS271
M	ZN602
M	MFN603

site_id	AI1
Number of Residues	5
Details	binding site for residue ZN M 602

Chain	Residue
M	HIS57
M	HIS59
M	KCX178
M	ASP385
M	ZN601

site_id	AI2
Number of Residues	19
Details	binding site for residue MFN M 603

Chain	Residue
M	HIS231
M	LEU235
M	HIS271
M	PHE274
M	TRP282
M	ARG283
M	THR316
M	MET323
M	GLU324
M	LEU330
M	PHE351
M	TYR353
M	VAL359
M	ASP385
M	ASN388
M	HIS417
M	TRP419
M	ARG422
M	ZN601

site_id	AI3
Number of Residues	2
Details	binding site for residue NA M 604

Chain	Residue
M	GLY144
M	ASN145

site_id	AI4
Number of Residues	4
Details	binding site for residue K M 605

Chain	Residue
M	ARG69
M	ARG72
M	SER76
N	GLY305

site_id	AI5
Number of Residues	3
Details	binding site for residue K M 606

Chain	Residue
M	VAL340
M	THR344
N	GLU138

site_id	AI6
Number of Residues	4
Details	binding site for residue SF4 N 501

Chain	Residue
N	CYS9
N	CYS12
N	CYS16
N	CYS35

site_id	AI7
Number of Residues	4
Details	binding site for residue W N 502

Chain	Residue
N	CYS118
N	MGD503
N	MGD504
N	H2S505

site_id	AI8
Number of Residues	30
Details	binding site for residue MGD N 503

Chain	Residue
N	LYS41
N	CYS91
N	VAL117
N	CYS118
N	MET254
N	HIS258
N	HIS290
N	ALA342
N	SER343
N	ASP344
N	HIS348
N	ILE365
N	GLU366
N	PRO367
N	HIS368
N	PRO382
N	ILE384
N	VAL385
N	ASP414
N	W502
N	MGD504
N	H2S505
N	HOH616
P	THR7
P	ARG9
P	LYS21
P	MET80
P	ASN85
P	PHE100
P	LYS101

site_id	AI9
Number of Residues	36
Details	binding site for residue MGD N 504

Chain	Residue
N	PHE11
N	ILE37
N	CYS118
N	GLY150
N	CYS151
N	ASN152
N	HIS155
N	ALA156
N	VAL184
N	ASP185
N	PRO186
N	ARG187
N	THR189
N	PHE203
N	ASP204
N	ASP206
N	GLY253
N	MET254
N	GLY255
N	SER259
N	GLY289
N	HIS290
N	W502
N	MGD503
N	H2S505
N	HOH607
N	HOH621
P	ASN6
P	GLY8
P	ARG9
P	THR10
P	GLN13
P	GLY14
P	MET80
P	LYS101
P	ASN102

site_id	AJ1
Number of Residues	6
Details	binding site for residue H2S N 505

Chain	Residue
N	THR114
N	CYS118
N	HIS290
N	W502
N	MGD503
N	MGD504

site_id	AJ2
Number of Residues	1
Details	binding site for residue CL N 506

Chain	Residue
N	ARG36

site_id	AJ3
Number of Residues	4
Details	binding site for residue K N 507

Chain	Residue
N	SER40
N	LYS41
N	VAL43
P	GLU18

site_id	AJ4
Number of Residues	7
Details	binding site for residue MG O 301

Chain	Residue
N	ASP128
O	SER139
O	TYR140
O	GLY142
O	ASP143
O	GLU164
O	TYR165

site_id	AJ5
Number of Residues	5
Details	binding site for residue SF4 Q 101

Chain	Residue
Q	CYS12
Q	CYS15
Q	GLY16
Q	CYS18
Q	CYS71

site_id	AJ6
Number of Residues	7
Details	binding site for residue SF4 Q 102

Chain	Residue
Q	CYS22
Q	ILE45
Q	CYS61
Q	GLY62
Q	CYS64
Q	GLY65
Q	CYS67

site_id	AJ7
Number of Residues	3
Details	binding site for residue K Q 103

Chain	Residue
Q	VAL68
Q	CYS71
Q	ASP74

site_id	AJ8
Number of Residues	5
Details	binding site for residue SF4 R 401

Chain	Residue
R	CYS281
R	CYS308
R	CYS311
R	GLY312
R	CYS314

site_id	AJ9
Number of Residues	4
Details	binding site for residue SF4 R 402

Chain	Residue
R	CYS271
R	CYS274
R	CYS277
R	CYS318

site_id	AK1
Number of Residues	7
Details	binding site for residue SF4 R 403

Chain	Residue
R	LEU24
R	CYS41
R	CYS71
R	LEU73
R	CYS74
R	GLY75
R	CYS77

site_id	AK2
Number of Residues	6
Details	binding site for residue SF4 R 404

Chain	Residue
R	CYS31
R	CYS34
R	GLY35
R	CYS37
R	CYS81
R	PHE83

site_id	AK3
Number of Residues	7
Details	binding site for residue SF4 R 405

Chain	Residue
R	CYS125
R	CYS239
R	VAL240
R	ASN241
R	CYS242
R	GLY243
R	CYS245

site_id	AK4
Number of Residues	5
Details	binding site for residue SF4 R 406

Chain	Residue
R	CYS115
R	CYS118
R	LYS119
R	CYS121
R	CYS249

site_id	AK5
Number of Residues	6
Details	binding site for residue SF4 R 407

Chain	Residue
R	CYS154
R	TYR156
R	CYS157
R	GLY158
R	CYS160
R	CYS204

site_id	AK6
Number of Residues	5
Details	binding site for residue SF4 R 408

Chain	Residue
R	CYS164
R	CYS194
R	CYS197
R	GLY198
R	CYS200

site_id	AK7
Number of Residues	4
Details	binding site for residue SF4 R 409

Chain	Residue
R	CYS213
R	CYS216
X	CYS213
X	CYS216

site_id	AK8
Number of Residues	4
Details	binding site for residue K R 410

Chain	Residue
R	GLU161
R	GLU162
R	CYS164
R	ASP167

site_id	AK9
Number of Residues	4
Details	binding site for residue K R 411

Chain	Residue
R	GLN246
R	GLU247
R	CYS249
R	ASP252

site_id	AL1
Number of Residues	3
Details	binding site for residue K R 412

Chain	Residue
R	LYS201
R	ARG202
R	CYS204

site_id	AL2
Number of Residues	5
Details	binding site for residue ZN S 601

Chain	Residue
S	KCX178
S	HIS231
S	HIS271
S	ZN602
S	MFN603

site_id	AL3
Number of Residues	5
Details	binding site for residue ZN S 602

Chain	Residue
S	HIS57
S	HIS59
S	KCX178
S	ASP385
S	ZN601

site_id	AL4
Number of Residues	20
Details	binding site for residue MFN S 603

Chain	Residue
S	HIS231
S	LEU235
S	HIS271
S	PHE274
S	TRP282
S	THR316
S	THR318
S	MET323
S	GLU324
S	PHE351
S	TYR353
S	VAL359
S	GLN363
S	ASP385
S	ASN388
S	HIS417
S	TRP419
S	ARG422
S	ZN601
S	HOH712

site_id	AL5
Number of Residues	5
Details	binding site for residue NA S 604

Chain	Residue
S	GLY144
S	ASN145
S	VAL180
S	HOH718
S	HOH737

site_id	AL6
Number of Residues	6
Details	binding site for residue K S 605

Chain	Residue
S	ARG69
S	ARG72
S	SER76
S	HOH710
S	HOH733
T	GLY305

site_id	AL7
Number of Residues	4
Details	binding site for residue K S 606

Chain	Residue
S	ILE412
S	GLU413
S	GLY414
S	LEU416

site_id	AL8
Number of Residues	4
Details	binding site for residue SF4 T 501

Chain	Residue
T	CYS9
T	CYS12
T	CYS16
T	CYS35

site_id	AL9
Number of Residues	4
Details	binding site for residue W T 502

Chain	Residue
T	CYS118
T	MGD503
T	MGD504
T	H2S505

site_id	AM1
Number of Residues	29
Details	binding site for residue MGD T 503

Chain	Residue
T	LYS41
T	CYS91
T	VAL117
T	CYS118
T	HIS258
T	HIS290
T	ALA342
T	SER343
T	ASP344
T	HIS348
T	ILE365
T	GLU366
T	PRO367
T	HIS368
T	PRO382
T	ILE384
T	VAL385
T	ASP414
T	W502
T	MGD504
T	H2S505
T	HOH609
V	THR7
V	ARG9
V	LYS21
V	MET80
V	ASN85
V	PHE100
V	LYS101

site_id	AM2
Number of Residues	35
Details	binding site for residue MGD T 504

Chain	Residue
T	PHE11
T	ILE37
T	CYS118
T	GLY150
T	CYS151
T	ASN152
T	HIS155
T	ALA156
T	VAL184
T	ASP185
T	PRO186
T	ARG187
T	PHE203
T	ASP204
T	ASP206
T	GLY253
T	MET254
T	GLY255
T	SER259
T	GLY289
T	HIS290
T	W502
T	MGD503
T	H2S505
T	HOH610
T	HOH624
V	ASN6
V	GLY8
V	ARG9
V	THR10
V	GLN13
V	GLY14
V	MET80
V	LYS101
V	ASN102

site_id	AM3
Number of Residues	6
Details	binding site for residue H2S T 505

Chain	Residue
T	THR114
T	CYS118
T	HIS290
T	W502
T	MGD503
T	MGD504

site_id	AM4
Number of Residues	4
Details	binding site for residue K T 506

Chain	Residue
T	SER40
T	LYS41
T	VAL43
V	GLU18

site_id	AM5
Number of Residues	7
Details	binding site for residue MG T 507

Chain	Residue
T	ASP128
U	SER139
U	TYR140
U	GLY142
U	ASP143
U	GLU164
U	TYR165

site_id	AM6
Number of Residues	7
Details	binding site for residue SF4 W 200

Chain	Residue
W	CYS12
W	HIS13
W	CYS15
W	GLY16
W	CYS18
W	CYS71
W	ALA75

site_id	AM7
Number of Residues	5
Details	binding site for residue SF4 W 201

Chain	Residue
W	CYS22
W	CYS61
W	CYS64
W	GLY65
W	CYS67

site_id	AM8
Number of Residues	6
Details	binding site for residue SF4 X 501

Chain	Residue
X	CYS154
X	TYR156
X	CYS157
X	GLY158
X	CYS160
X	CYS204

site_id	AM9
Number of Residues	6
Details	binding site for residue SF4 X 502

Chain	Residue
X	CYS164
X	CYS194
X	HIS196
X	CYS197
X	GLY198
X	CYS200

site_id	AN1
Number of Residues	6
Details	binding site for residue SF4 X 503

Chain	Residue
X	CYS281
X	CYS308
X	TYR310
X	CYS311
X	GLY312
X	CYS314

site_id	AN2
Number of Residues	7
Details	binding site for residue SF4 X 504

Chain	Residue
X	CYS271
X	GLN272
X	ALA273
X	CYS274
X	GLU275
X	CYS277
X	CYS318

site_id	AN3
Number of Residues	8
Details	binding site for residue SF4 X 505

Chain	Residue
X	CYS41
X	ALA45
X	CYS71
X	VAL72
X	LEU73
X	CYS74
X	GLY75
X	CYS77

site_id	AN4
Number of Residues	5
Details	binding site for residue SF4 X 506

Chain	Residue
X	CYS31
X	CYS34
X	GLY35
X	CYS37
X	CYS81

site_id	AN5
Number of Residues	7
Details	binding site for residue SF4 X 507

Chain	Residue
X	CYS125
X	CYS239
X	VAL240
X	ASN241
X	CYS242
X	GLY243
X	CYS245

site_id	AN6
Number of Residues	5
Details	binding site for residue SF4 X 508

Chain	Residue
X	CYS115
X	CYS118
X	LYS119
X	CYS121
X	CYS249

site_id	AN7
Number of Residues	4
Details	binding site for residue K X 509

Chain	Residue
X	GLU122
X	THR123
X	CYS125
X	ASP128

site_id	AN8
Number of Residues	4
Details	binding site for residue K X 510

Chain	Residue
X	GLU161
X	GLU162
X	CYS164
X	ASP167

site_id	AN9
Number of Residues	4
Details	binding site for residue K X 511

Chain	Residue
X	GLN246
X	GLU247
X	CYS249
X	ASP252

site_id	AO1
Number of Residues	5
Details	binding site for residue ZN Y 601

Chain	Residue
Y	KCX178
Y	HIS231
Y	HIS271
Y	ZN602
Y	MFN603

site_id	AO2
Number of Residues	5
Details	binding site for residue ZN Y 602

Chain	Residue
Y	HIS57
Y	HIS59
Y	KCX178
Y	ASP385
Y	ZN601

site_id	AO3
Number of Residues	20
Details	binding site for residue MFN Y 603

Chain	Residue
Y	HIS231
Y	LEU235
Y	HIS271
Y	PHE274
Y	TRP282
Y	ARG283
Y	THR318
Y	MET323
Y	GLU324
Y	PHE351
Y	TYR353
Y	VAL359
Y	GLN363
Y	ASP385
Y	ASN388
Y	HIS417
Y	LYS418
Y	TRP419
Y	ARG422
Y	ZN601

site_id	AO4
Number of Residues	4
Details	binding site for residue K Y 604

Chain	Residue
Y	ARG69
Y	ARG72
Y	SER76
Z	GLY305

site_id	AO5
Number of Residues	4
Details	binding site for residue SF4 Z 501

Chain	Residue
Z	CYS9
Z	CYS12
Z	CYS16
Z	CYS35

site_id	AO6
Number of Residues	4
Details	binding site for residue W Z 502

Chain	Residue
Z	CYS118
Z	MGD503
Z	MGD504
Z	H2S505

site_id	AO7
Number of Residues	29
Details	binding site for residue MGD Z 503

Chain	Residue
Z	LYS41
Z	CYS91
Z	VAL117
Z	CYS118
Z	HIS258
Z	HIS290
Z	ALA342
Z	SER343
Z	ASP344
Z	HIS348
Z	ILE365
Z	GLU366
Z	PRO367
Z	HIS368
Z	PRO382
Z	ALA383
Z	ILE384
Z	VAL385
Z	ASP414
Z	W502
Z	MGD504
Z	H2S505
b	THR7
b	ARG9
b	LYS21
b	MET80
b	ASN85
b	PHE100
b	LYS101

site_id	AO8
Number of Residues	36
Details	binding site for residue MGD Z 504

Chain	Residue
Z	PHE11
Z	ILE37
Z	CYS118
Z	GLY150
Z	CYS151
Z	ASN152
Z	HIS155
Z	ALA156
Z	HIS157
Z	VAL184
Z	ASP185
Z	PRO186
Z	ARG187
Z	PHE203
Z	ASP204
Z	ASP206
Z	GLY253
Z	MET254
Z	GLY255
Z	SER259
Z	GLY289
Z	HIS290
Z	W502
Z	MGD503
Z	H2S505
Z	HOH602
b	ASN6
b	GLY8
b	ARG9
b	THR10
b	GLN13
b	GLY14
b	ILE17
b	MET80
b	LYS101
b	ASN102

site_id	AO9
Number of Residues	6
Details	binding site for residue H2S Z 505

Chain	Residue
Z	CYS118
Z	GLY289
Z	HIS290
Z	W502
Z	MGD503
Z	MGD504

site_id	AP1
Number of Residues	4
Details	binding site for residue K Z 506

Chain	Residue
Z	SER40
Z	LYS41
Z	VAL43
b	GLU18

site_id	AP2
Number of Residues	6
Details	binding site for residue MG Z 507

Chain	Residue
Z	ASP128
a	SER139
a	TYR140
a	ASP143
a	GLU164
a	TYR165

site_id	AP3
Number of Residues	6
Details	binding site for residue SF4 c 101

Chain	Residue
c	CYS12
c	CYS15
c	GLY16
c	CYS18
c	CYS71
c	ALA75

site_id	AP4
Number of Residues	6
Details	binding site for residue SF4 c 102

Chain	Residue
c	CYS22
c	ILE45
c	CYS61
c	CYS64
c	GLY65
c	CYS67

site_id	AP5
Number of Residues	3
Details	binding site for residue K c 103

Chain	Residue
c	VAL68
c	CYS71
c	ASP74

site_id	AP6
Number of Residues	5
Details	binding site for residue SF4 d 401

Chain	Residue
d	CYS281
d	CYS308
d	CYS311
d	GLY312
d	CYS314

site_id	AP7
Number of Residues	5
Details	binding site for residue SF4 d 402

Chain	Residue
d	CYS271
d	ALA273
d	CYS274
d	CYS277
d	CYS318

site_id	AP8
Number of Residues	8
Details	binding site for residue SF4 d 403

Chain	Residue
d	CYS41
d	PRO42
d	VAL43
d	CYS71
d	LEU73
d	CYS74
d	GLY75
d	CYS77

site_id	AP9
Number of Residues	5
Details	binding site for residue SF4 d 404

Chain	Residue
d	CYS31
d	CYS34
d	GLY35
d	CYS37
d	CYS81

site_id	AQ1
Number of Residues	7
Details	binding site for residue SF4 d 405

Chain	Residue
d	CYS125
d	ILE130
d	CYS239
d	VAL240
d	ASN241
d	CYS242
d	CYS245

site_id	AQ2
Number of Residues	5
Details	binding site for residue SF4 d 406

Chain	Residue
d	CYS115
d	CYS118
d	LYS119
d	CYS121
d	CYS249

site_id	AQ3
Number of Residues	5
Details	binding site for residue SF4 d 407

Chain	Residue
d	CYS213
d	CYS216
j	CYS213
j	ILE215
j	CYS216

site_id	AQ4
Number of Residues	4
Details	binding site for residue SF4 d 408

Chain	Residue
d	CYS154
d	CYS157
d	CYS160
d	CYS204

site_id	AQ5
Number of Residues	6
Details	binding site for residue SF4 d 409

Chain	Residue
d	CYS200
d	CYS164
d	CYS194
d	HIS196
d	CYS197
d	GLY198

site_id	AQ6
Number of Residues	4
Details	binding site for residue K d 410

Chain	Residue
d	GLU161
d	GLU162
d	CYS164
d	ASP167

site_id	AQ7
Number of Residues	4
Details	binding site for residue K d 411

Chain	Residue
d	GLN246
d	GLU247
d	CYS249
d	ASP252

site_id	AQ8
Number of Residues	5
Details	binding site for residue ZN e 601

Chain	Residue
e	KCX178
e	HIS231
e	HIS271
e	ZN602
e	MFN603

site_id	AQ9
Number of Residues	5
Details	binding site for residue ZN e 602

Chain	Residue
e	HIS57
e	HIS59
e	KCX178
e	ASP385
e	ZN601

site_id	AR1
Number of Residues	18
Details	binding site for residue MFN e 603

Chain	Residue
e	HIS231
e	LEU235
e	GLY236
e	HIS271
e	PHE274
e	TRP282
e	ARG283
e	THR316
e	THR318
e	MET323
e	GLU324
e	TYR353
e	GLN363
e	ASP385
e	ASN388
e	HIS417
e	TRP419
e	ZN601

site_id	AR2
Number of Residues	5
Details	binding site for residue NA e 604

Chain	Residue
e	LEU142
e	GLY144
e	ASN145
e	VAL180
e	HOH712

site_id	AR3
Number of Residues	6
Details	binding site for residue K e 605

Chain	Residue
e	VAL340
e	THR344
e	HOH715
e	HOH716
f	GLU138
f	ARG142

site_id	AR4
Number of Residues	5
Details	binding site for residue K e 606

Chain	Residue
e	ARG69
e	ARG72
e	SER76
e	HOH704
f	GLY305

site_id	AR5
Number of Residues	4
Details	binding site for residue K e 607

Chain	Residue
e	ILE412
e	GLU413
e	GLY414
e	LEU416

site_id	AR6
Number of Residues	4
Details	binding site for residue K e 608

Chain	Residue
e	ASP264
e	ASP300
e	HOH717
e	HOH740

site_id	AR7
Number of Residues	4
Details	binding site for residue SF4 f 501

Chain	Residue
f	CYS9
f	CYS12
f	CYS16
f	CYS35

site_id	AR8
Number of Residues	4
Details	binding site for residue W f 502

Chain	Residue
f	CYS118
f	MGD503
f	MGD504
f	H2S505

site_id	AR9
Number of Residues	29
Details	binding site for residue MGD f 503

Chain	Residue
f	LYS41
f	CYS91
f	VAL117
f	CYS118
f	HIS258
f	HIS290
f	ALA342
f	SER343
f	ASP344
f	HIS348
f	ILE365
f	GLU366
f	PRO367
f	HIS368
f	THR370
f	PRO382
f	ILE384
f	VAL385
f	ASP414
f	W502
f	MGD504
f	H2S505
h	THR7
h	ARG9
h	LYS21
h	MET80
h	ASN85
h	PHE100
h	LYS101

site_id	AS1
Number of Residues	34
Details	binding site for residue MGD f 504

Chain	Residue
f	PHE11
f	ILE37
f	CYS118
f	GLY150
f	CYS151
f	ASN152
f	HIS155
f	ALA156
f	VAL184
f	ASP185
f	PRO186
f	ARG187
f	PHE203
f	ASP204
f	ASP206
f	GLY253
f	MET254
f	GLY255
f	SER259
f	GLY289
f	HIS290
f	W502
f	MGD503
f	H2S505
f	HOH606
h	ASN6
h	GLY8
h	ARG9
h	THR10
h	GLN13
h	GLY14
h	MET80
h	LYS101
h	ASN102

site_id	AS2
Number of Residues	6
Details	binding site for residue H2S f 505

Chain	Residue
f	THR114
f	CYS118
f	HIS290
f	W502
f	MGD503
f	MGD504

site_id	AS3
Number of Residues	7
Details	binding site for residue MG f 506

Chain	Residue
f	ASP128
g	SER139
g	TYR140
g	GLY142
g	ASP143
g	GLU164
g	TYR165

site_id	AS4
Number of Residues	7
Details	binding site for residue SF4 i 101

Chain	Residue
i	CYS12
i	HIS13
i	CYS15
i	GLY16
i	CYS18
i	CYS71
i	ALA75

site_id	AS5
Number of Residues	7
Details	binding site for residue SF4 i 102

Chain	Residue
i	CYS22
i	MET46
i	CYS61
i	GLY62
i	CYS64
i	GLY65
i	CYS67

site_id	AS6
Number of Residues	3
Details	binding site for residue K i 103

Chain	Residue
i	VAL68
i	CYS71
i	ASP74

site_id	AS7
Number of Residues	4
Details	binding site for residue SF4 j 501

Chain	Residue
j	CYS154
j	CYS157
j	CYS160
j	CYS204

site_id	AS8
Number of Residues	5
Details	binding site for residue SF4 j 502

Chain	Residue
j	CYS164
j	CYS194
j	CYS197
j	GLY198
j	CYS200

site_id	AS9
Number of Residues	5
Details	binding site for residue SF4 j 503

Chain	Residue
j	CYS281
j	VAL285
j	CYS308
j	CYS311
j	CYS314

site_id	AT1
Number of Residues	7
Details	binding site for residue SF4 j 504

Chain	Residue
j	CYS271
j	GLN272
j	ALA273
j	CYS274
j	GLU275
j	CYS277
j	CYS318

site_id	AT2
Number of Residues	6
Details	binding site for residue SF4 j 505

Chain	Residue
j	CYS41
j	CYS71
j	LEU73
j	CYS74
j	GLY75
j	CYS77

site_id	AT3
Number of Residues	6
Details	binding site for residue SF4 j 506

Chain	Residue
j	CYS31
j	CYS34
j	GLY35
j	CYS37
j	CYS81
j	PHE83

site_id	AT4
Number of Residues	7
Details	binding site for residue SF4 j 507

Chain	Residue
j	CYS125
j	CYS239
j	VAL240
j	ASN241
j	CYS242
j	GLY243
j	CYS245

site_id	AT5
Number of Residues	5
Details	binding site for residue SF4 j 508

Chain	Residue
j	CYS115
j	CYS118
j	LYS119
j	CYS121
j	CYS249

site_id	AT6
Number of Residues	4
Details	binding site for residue K j 509

Chain	Residue
j	GLU161
j	GLU162
j	CYS164
j	ASP167

site_id	AT7
Number of Residues	4
Details	binding site for residue K j 510

Chain	Residue
j	GLN246
j	GLU247
j	CYS249
j	ASP252

site_id	AT8
Number of Residues	4
Details	binding site for residue K j 511

Chain	Residue
j	GLU122
j	THR123
j	CYS125
j	ASP128

site_id	AT9
Number of Residues	3
Details	binding site for residue K j 512

Chain	Residue
a	LYS229
j	ILE110
j	ASP112

site_id	AU1
Number of Residues	4
Details	binding site for residue K j 513

Chain	Residue
j	LYS201
j	ARG202
j	CYS204
j	ASP207

site_id	AU2
Number of Residues	2
Details	binding site for residue K j 514

Chain	Residue
j	HIS196
j	CYS213

site_id	AU3
Number of Residues	5
Details	binding site for residue ZN k 601

Chain	Residue
k	KCX178
k	HIS231
k	HIS271
k	ZN602
k	MFN603

site_id	AU4
Number of Residues	6
Details	binding site for residue ZN k 602

Chain	Residue
k	HIS57
k	HIS59
k	KCX178
k	ASP385
k	ZN601
k	MFN603

site_id	AU5
Number of Residues	20
Details	binding site for residue MFN k 603

Chain	Residue
k	HIS231
k	LEU235
k	HIS271
k	PHE274
k	TRP282
k	ARG283
k	THR318
k	MET323
k	LEU330
k	PHE351
k	TYR353
k	PRO358
k	VAL359
k	GLN363
k	ASP385
k	ASN388
k	HIS417
k	TRP419
k	ZN601
k	ZN602

site_id	AU6
Number of Residues	3
Details	binding site for residue NA k 604

Chain	Residue
k	ASN145
k	THR344
k	HOH709

site_id	AU7
Number of Residues	5
Details	binding site for residue K k 605

Chain	Residue
k	ARG69
k	ARG72
k	SER76
k	HOH705
l	GLY305

site_id	AU8
Number of Residues	4
Details	binding site for residue SF4 l 501

Chain	Residue
l	CYS9
l	CYS12
l	CYS16
l	CYS35

site_id	AU9
Number of Residues	4
Details	binding site for residue W l 502

Chain	Residue
l	CYS118
l	MGD503
l	MGD504
l	H2S505

site_id	AV1
Number of Residues	30
Details	binding site for residue MGD l 503

Chain	Residue
l	LYS41
l	CYS91
l	VAL117
l	CYS118
l	MET254
l	HIS258
l	HIS290
l	ALA342
l	SER343
l	ASP344
l	HIS348
l	ILE365
l	GLU366
l	PRO367
l	HIS368
l	PRO382
l	ALA383
l	ILE384
l	VAL385
l	ASP414
l	W502
l	MGD504
l	H2S505
n	THR7
n	ARG9
n	LYS21
n	MET80
n	ASN85
n	PHE100
n	LYS101

site_id	AV2
Number of Residues	36
Details	binding site for residue MGD l 504

Chain	Residue
l	PHE11
l	ILE37
l	CYS118
l	GLY150
l	CYS151
l	ASN152
l	HIS155
l	ALA156
l	VAL184
l	ASP185
l	PRO186
l	ARG187
l	THR189
l	PHE203
l	ASP204
l	ASP206
l	GLY253
l	MET254
l	GLY255
l	SER259
l	GLY289
l	HIS290
l	W502
l	MGD503
l	H2S505
l	HOH609
l	HOH610
n	ASN6
n	GLY8
n	ARG9
n	THR10
n	GLN13
n	GLY14
n	MET80
n	LYS101
n	ASN102

site_id	AV3
Number of Residues	5
Details	binding site for residue H2S l 505

Chain	Residue
l	CYS118
l	HIS290
l	W502
l	MGD503
l	MGD504

site_id	AV4
Number of Residues	7
Details	binding site for residue MG l 506

Chain	Residue
l	ASP128
m	SER139
m	TYR140
m	GLY142
m	ASP143
m	GLU164
m	TYR165

site_id	AV5
Number of Residues	7
Details	binding site for residue SF4 o 101

Chain	Residue
o	CYS12
o	HIS13
o	CYS15
o	GLY16
o	CYS18
o	CYS71
o	ALA75

site_id	AV6
Number of Residues	5
Details	binding site for residue SF4 o 102

Chain	Residue
o	CYS22
o	CYS61
o	CYS64
o	GLY65
o	CYS67

site_id	AV7
Number of Residues	3
Details	binding site for residue K o 103

Chain	Residue
o	VAL68
o	CYS71
o	ASP74

site_id	AV8
Number of Residues	6
Details	binding site for residue SF4 p 401

Chain	Residue
p	CYS281
p	CYS308
p	TYR310
p	CYS311
p	GLY312
p	CYS314

site_id	AV9
Number of Residues	6
Details	binding site for residue SF4 p 402

Chain	Residue
p	CYS271
p	ALA273
p	CYS274
p	GLU275
p	CYS277
p	CYS318

site_id	AW1
Number of Residues	5
Details	binding site for residue SF4 p 403

Chain	Residue
p	CYS41
p	CYS71
p	CYS74
p	GLY75
p	CYS77

site_id	AW2
Number of Residues	5
Details	binding site for residue SF4 p 404

Chain	Residue
p	CYS31
p	CYS34
p	GLY35
p	CYS37
p	CYS81

site_id	AW3
Number of Residues	7
Details	binding site for residue SF4 p 405

Chain	Residue
p	CYS125
p	CYS239
p	VAL240
p	ASN241
p	CYS242
p	GLY243
p	CYS245

site_id	AW4
Number of Residues	5
Details	binding site for residue SF4 p 406

Chain	Residue
p	CYS115
p	CYS118
p	LYS119
p	CYS121
p	CYS249

site_id	AW5
Number of Residues	4
Details	binding site for residue SF4 p 407

Chain	Residue
p	CYS154
p	CYS157
p	CYS160
p	CYS204

site_id	AW6
Number of Residues	6
Details	binding site for residue SF4 p 408

Chain	Residue
p	CYS164
p	CYS194
p	HIS196
p	CYS197
p	GLY198
p	CYS200

site_id	AW7
Number of Residues	4
Details	binding site for residue SF4 p 409

Chain	Residue
p	CYS213
p	CYS216
v	CYS213
v	CYS216

site_id	AW8
Number of Residues	4
Details	binding site for residue K p 410

Chain	Residue
p	GLU161
p	GLU162
p	CYS164
p	ASP167

site_id	AW9
Number of Residues	4
Details	binding site for residue K p 411

Chain	Residue
p	GLU122
p	THR123
p	CYS125
p	ASP128

site_id	AX1
Number of Residues	4
Details	binding site for residue K p 412

Chain	Residue
p	GLN246
p	GLU247
p	CYS249
p	ASP252

site_id	AX2
Number of Residues	5
Details	binding site for residue ZN q 601

Chain	Residue
q	KCX178
q	HIS231
q	HIS271
q	ZN602
q	MFN603

site_id	AX3
Number of Residues	5
Details	binding site for residue ZN q 602

Chain	Residue
q	HIS57
q	HIS59
q	KCX178
q	ASP385
q	ZN601

site_id	AX4
Number of Residues	19
Details	binding site for residue MFN q 603

Chain	Residue
q	HIS231
q	LEU235
q	PHE274
q	TRP282
q	ARG283
q	THR316
q	THR318
q	MET323
q	GLU324
q	LEU330
q	PHE351
q	TYR353
q	VAL359
q	GLN363
q	ASP385
q	ASN388
q	HIS417
q	TRP419
q	ZN601

site_id	AX5
Number of Residues	2
Details	binding site for residue NA q 604

Chain	Residue
q	ASN145
q	VAL180

site_id	AX6
Number of Residues	5
Details	binding site for residue K q 605

Chain	Residue
q	VAL340
q	THR344
q	HOH702
q	HOH720
r	GLU138

site_id	AX7
Number of Residues	4
Details	binding site for residue K q 606

Chain	Residue
q	ARG69
q	ARG72
q	SER76
r	GLY305

site_id	AX8
Number of Residues	4
Details	binding site for residue SF4 r 501

Chain	Residue
r	CYS9
r	CYS12
r	CYS16
r	CYS35

site_id	AX9
Number of Residues	4
Details	binding site for residue W r 502

Chain	Residue
r	CYS118
r	MGD503
r	MGD504
r	H2S505

site_id	AY1
Number of Residues	29
Details	binding site for residue MGD r 503

Chain	Residue
r	LYS41
r	CYS91
r	VAL117
r	CYS118
r	HIS258
r	HIS290
r	ILE341
r	ALA342
r	SER343
r	ASP344
r	HIS348
r	ILE365
r	GLU366
r	HIS368
r	THR370
r	ILE384
r	VAL385
r	ASP414
r	W502
r	MGD504
r	H2S505
r	HOH608
t	THR7
t	ARG9
t	LYS21
t	MET80
t	ASN85
t	PHE100
t	LYS101

site_id	AY2
Number of Residues	35
Details	binding site for residue MGD r 504

Chain	Residue
r	PHE11
r	ILE37
r	CYS118
r	GLY150
r	CYS151
r	ASN152
r	HIS155
r	ALA156
r	VAL184
r	ASP185
r	PRO186
r	ARG187
r	PHE203
r	ASP204
r	ASP206
r	GLY253
r	MET254
r	GLY255
r	SER259
r	GLY289
r	HIS290
r	W502
r	MGD503
r	H2S505
r	HOH612
t	ASN6
t	GLY8
t	ARG9
t	THR10
t	GLN13
t	GLY14
t	ILE17
t	MET80
t	LYS101
t	ASN102

site_id	AY3
Number of Residues	6
Details	binding site for residue H2S r 505

Chain	Residue
r	THR114
r	CYS118
r	HIS290
r	W502
r	MGD503
r	MGD504

site_id	AY4
Number of Residues	4
Details	binding site for residue K r 506

Chain	Residue
r	SER40
r	LYS41
r	VAL43
t	GLU18

site_id	AY5
Number of Residues	7
Details	binding site for residue MG r 507

Chain	Residue
r	ASP128
s	SER139
s	TYR140
s	GLY142
s	ASP143
s	GLU164
s	TYR165

site_id	AY6
Number of Residues	7
Details	binding site for residue SF4 u 101

Chain	Residue
u	CYS12
u	HIS13
u	CYS15
u	GLY16
u	CYS18
u	CYS71
u	ALA75

site_id	AY7
Number of Residues	6
Details	binding site for residue SF4 u 102

Chain	Residue
u	CYS22
u	MET46
u	CYS61
u	CYS64
u	GLY65
u	CYS67

site_id	AY8
Number of Residues	3
Details	binding site for residue K u 103

Chain	Residue
u	VAL68
u	CYS71
u	ASP74

site_id	AY9
Number of Residues	5
Details	binding site for residue SF4 v 501

Chain	Residue
v	CYS154
v	TYR156
v	CYS157
v	CYS160
v	CYS204

site_id	AZ1
Number of Residues	5
Details	binding site for residue SF4 v 502

Chain	Residue
v	CYS164
v	CYS194
v	CYS197
v	GLY198
v	CYS200

site_id	AZ2
Number of Residues	7
Details	binding site for residue SF4 v 503

Chain	Residue
v	CYS281
v	VAL285
v	CYS308
v	TYR310
v	CYS311
v	GLY312
v	CYS314

site_id	AZ3
Number of Residues	6
Details	binding site for residue SF4 v 504

Chain	Residue
v	CYS271
v	GLN272
v	ALA273
v	CYS274
v	CYS277
v	CYS318

site_id	AZ4
Number of Residues	6
Details	binding site for residue SF4 v 505

Chain	Residue
v	CYS41
v	CYS71
v	LEU73
v	CYS74
v	GLY75
v	CYS77

site_id	AZ5
Number of Residues	5
Details	binding site for residue SF4 v 506

Chain	Residue
v	CYS31
v	CYS34
v	GLY35
v	CYS37
v	CYS81

site_id	AZ6
Number of Residues	7
Details	binding site for residue SF4 v 507

Chain	Residue
v	CYS125
v	CYS239
v	VAL240
v	ASN241
v	CYS242
v	GLY243
v	CYS245

site_id	AZ7
Number of Residues	5
Details	binding site for residue SF4 v 508

Chain	Residue
v	CYS115
v	CYS118
v	LYS119
v	CYS121
v	CYS249

site_id	AZ8
Number of Residues	4
Details	binding site for residue K v 509

Chain	Residue
v	GLU122
v	THR123
v	CYS125
v	ASP128

site_id	AZ9
Number of Residues	4
Details	binding site for residue K v 510

Chain	Residue
v	GLN246
v	GLU247
v	CYS249
v	ASP252

site_id	BC1
Number of Residues	3
Details	binding site for residue K v 511

Chain	Residue
v	GLU315
v	ARG316
v	CYS318

site_id	BC2
Number of Residues	4
Details	binding site for residue K v 512

Chain	Residue
v	GLU161
v	GLU162
v	CYS164
v	ASP167

site_id	BC3
Number of Residues	4
Details	binding site for residue K v 513

Chain	Residue
v	LYS201
v	ARG202
v	CYS204
v	ASP207

site_id	BC4
Number of Residues	3
Details	binding site for residue K v 514

Chain	Residue
v	VAL195
v	HIS196
v	CYS213

site_id	BC5
Number of Residues	3
Details	binding site for residue K v 515

Chain	Residue
v	LYS151
v	ASP152
v	CYS154

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CaVCGlCGeICP

Chain	Residue	Details
d	CYS31-PRO42
c	CYS61-PRO72
d	CYS71-PRO82
d	CYS115-PRO126
d	CYS154-PRO165
d	CYS194-PRO205
d	CYS239-PRO250
d	CYS271-PRO282
d	CYS308-PRO319
c	CYS12-PRO23

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)