5T3O

Crystal structure of the Phosphorybosylpyrophosphate synthetase II from Thermus thermophilus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0002189	cellular_component	ribose phosphate diphosphokinase complex
A	0004749	molecular_function	ribose phosphate diphosphokinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
A	0009165	biological_process	nucleotide biosynthetic process
A	0016301	molecular_function	kinase activity
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0002189	cellular_component	ribose phosphate diphosphokinase complex
B	0004749	molecular_function	ribose phosphate diphosphokinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
B	0009165	biological_process	nucleotide biosynthetic process
B	0016301	molecular_function	kinase activity
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0002189	cellular_component	ribose phosphate diphosphokinase complex
C	0004749	molecular_function	ribose phosphate diphosphokinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006015	biological_process	5-phosphoribose 1-diphosphate biosynthetic process
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0009156	biological_process	ribonucleoside monophosphate biosynthetic process
C	0009165	biological_process	nucleotide biosynthetic process
C	0016301	molecular_function	kinase activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue ADP A 401

Chain	Residue
A	SER94
C	ASN38
C	ASN40
A	ARG97
A	SER98
A	LYS100
A	ASP102
A	HIS131
A	ASP171
A	ARG196
C	PHE36

---

site_id	AC2
Number of Residues	7
Details	binding site for residue SO4 A 402

Chain	Residue
A	ARG105
A	SER304
A	VAL305
A	SER306
C	SER48
C	ARG50
C	HOH519

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 403

Chain	Residue
A	SER224
A	THR225
A	ALA226
A	GLY227
A	SER228

---

site_id	AC4
Number of Residues	12
Details	binding site for residue ADP B 401

Chain	Residue
B	PHE36
B	ASN38
B	ASN40
B	ARG97
B	SER98
B	LYS100
B	ASP102
B	HIS131
B	ASP171
B	ARG196
B	HOH552
B	HOH585

---

site_id	AC5
Number of Residues	8
Details	binding site for residue SO4 B 402

Chain	Residue
A	SER48
A	ARG50
B	SER304
B	VAL305
B	SER306
B	HOH529
B	HOH575
C	ARG105

---

site_id	AC6
Number of Residues	9
Details	binding site for residue SO4 B 403

Chain	Residue
B	ARG196
B	SER224
B	THR225
B	ALA226
B	GLY227
B	SER228
B	HOH515
B	HOH556
B	HOH567

---

site_id	AC7
Number of Residues	8
Details	binding site for residue ADP C 401

Chain	Residue
A	PHE36
A	ASN38
A	ASN40
C	ARG97
C	SER98
C	LYS100
C	ASP102
C	HIS131

---

site_id	AC8
Number of Residues	8
Details	binding site for residue SO4 C 402

Chain	Residue
B	SER48
B	ARG50
B	ARG105
B	HOH524
C	SER304
C	VAL305
C	SER306
C	HOH540

---

site_id	AC9
Number of Residues	7
Details	binding site for residue SO4 C 403

Chain	Residue
C	SER224
C	THR225
C	ALA226
C	GLY227
C	SER228
C	HOH520
C	HOH529

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