5T2K

Geobacillus stearothermophilus HemQ with Manganese-Coproporphyrin III

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0006783	biological_process	heme biosynthetic process
A	0006785	biological_process	heme B biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016634	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0006783	biological_process	heme biosynthetic process
B	0006785	biological_process	heme B biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016634	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0006783	biological_process	heme biosynthetic process
C	0006785	biological_process	heme B biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016634	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0006783	biological_process	heme biosynthetic process
D	0006785	biological_process	heme B biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016634	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
D	0098869	biological_process	cellular oxidant detoxification
E	0004601	molecular_function	peroxidase activity
E	0006783	biological_process	heme biosynthetic process
E	0006785	biological_process	heme B biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016634	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
E	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	binding site for residue 76R A 301

Chain	Residue
A	TYR113
A	GLN184
A	ILE186
A	TRP197
A	MET216
A	SER222
A	PHE228
A	HOH402
A	HOH430
A	HOH466
A	HOH542
A	ARG130
A	HOH554
A	HOH572
A	TYR144
A	LYS148
A	TRP156
A	MET168
A	HIS171
A	GLY175
A	ARG176

---

site_id	AC2
Number of Residues	22
Details	binding site for residue 76R B 301

Chain	Residue
B	SER111
B	TYR113
B	ARG130
B	TYR144
B	LYS148
B	TRP156
B	MET168
B	HIS171
B	GLY175
B	ARG176
B	GLN184
B	ILE186
B	TRP197
B	MET216
B	SER222
B	PHE228
B	HOH405
B	HOH426
B	HOH447
B	HOH451
B	HOH461
B	HOH525

---

site_id	AC3
Number of Residues	23
Details	binding site for residue 76R C 301

Chain	Residue
C	SER111
C	ARG130
C	TYR144
C	MET146
C	LYS148
C	TRP156
C	MET168
C	HIS171
C	GLY172
C	GLY175
C	ARG176
C	GLN184
C	ILE186
C	TRP197
C	MET216
C	SER222
C	PHE228
C	HOH413
C	HOH452
C	HOH488
C	HOH508
C	HOH539
C	HOH581

---

site_id	AC4
Number of Residues	22
Details	binding site for residue 76R D 301

Chain	Residue
D	SER111
D	TYR113
D	TYR144
D	MET146
D	LYS148
D	TRP156
D	MET168
D	HIS171
D	GLY172
D	GLY175
D	ARG176
D	GLN184
D	ILE186
D	TRP197
D	MET216
D	SER222
D	PHE228
D	HOH414
D	HOH431
D	HOH454
D	HOH485
D	HOH506

---

site_id	AC5
Number of Residues	20
Details	binding site for residue 76R E 301

Chain	Residue
E	TRP197
E	MET216
E	SER222
E	PHE228
E	HOH408
E	HOH445
E	HOH449
E	HOH527
E	HOH588
E	TYR113
E	ARG130
E	TYR144
E	LYS148
E	TRP156
E	MET168
E	HIS171
E	GLY175
E	ARG176
E	GLN184
E	ILE186

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01442","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01442","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27936663","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01442","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"27936663","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"HAMAP-Rule","id":"MF_01442","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"27936663","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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