5T16

Crystal structure of yeast RNase III (Rnt1p) complexed with a non-hydrolyzable RNA substrate analog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003725	molecular_function	double-stranded RNA binding
A	0004525	molecular_function	ribonuclease III activity
A	0006364	biological_process	rRNA processing
A	0006396	biological_process	RNA processing
B	0003725	molecular_function	double-stranded RNA binding
B	0004525	molecular_function	ribonuclease III activity
B	0006364	biological_process	rRNA processing
B	0006396	biological_process	RNA processing
I	0003725	molecular_function	double-stranded RNA binding
I	0004525	molecular_function	ribonuclease III activity
I	0006364	biological_process	rRNA processing
I	0006396	biological_process	RNA processing
J	0003725	molecular_function	double-stranded RNA binding
J	0004525	molecular_function	ribonuclease III activity
J	0006364	biological_process	rRNA processing
J	0006396	biological_process	RNA processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue EDO A 501

Chain	Residue
A	TYR226

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site_id	AC2
Number of Residues	2
Details	binding site for residue EDO E 201

Chain	Residue
E	ARG85
F	ASN43

---

site_id	AC3
Number of Residues	4
Details	binding site for residue EDO F 201

Chain	Residue
E	LYS113
E	ALA115
F	ILE116
F	GLU138

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO H 101

Chain	Residue
A	ASN306
H	G11
H	U12
A	PHE298
A	SER305

---

site_id	AC5
Number of Residues	4
Details	binding site for residue EDO I 501

Chain	Residue
I	ARG213
I	ASN234
I	HIS236
I	ARG239

---

site_id	AC6
Number of Residues	3
Details	binding site for residue EDO I 502

Chain	Residue
I	SER250
I	LEU254
I	ARG339

---

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO I 503

Chain	Residue
I	ARG239
I	GLU328
I	HOH641

---

site_id	AC8
Number of Residues	3
Details	binding site for residue EDO I 504

Chain	Residue
I	TYR226
I	SER228
N	HOH201

---

site_id	AC9
Number of Residues	1
Details	binding site for residue EDO I 505

Chain	Residue
I	ASP408

---

site_id	AD1
Number of Residues	3
Details	binding site for residue EDO J 501

Chain	Residue
J	THR394
J	ALA395
J	VAL396

---

Functional Information from PROSITE/UniProt

site_id	PS00517
Number of Residues	9
Details	RNASE_3_1 Ribonuclease III family signature. ERLEFLGDS

Chain	Residue	Details
A	GLU238-SER246

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	416
Details	Domain: {"description":"RNase III","evidences":[{"source":"PROSITE-ProRule","id":"PRU00177","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	272
Details	Domain: {"description":"DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00266","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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