5T13

Structure of the Cyanuric Acid Hydrolase TrzD Reveals Product Exit Channel

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A	0018753	molecular_function	cyanuric acid amidohydrolase activity
A	0019381	biological_process	atrazine catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue CO2 A 401

Chain	Residue
A	SER82
A	GLY83
A	SER233
A	ARG330
A	SER349
A	GLY350
A	HOH577
A	HOH638

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CO2 A 402

Chain	Residue
A	GLY235
A	ILE236
A	GLU237
A	HOH589
A	ARG51

---

site_id	AC3
Number of Residues	7
Details	binding site for residue MG A 403

Chain	Residue
A	GLU303
A	SER352
A	GLN355
A	GLY356
A	PRO357
A	GLY360
A	HOH634

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	102
Details	Region: {"description":"RU A","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	137
Details	Region: {"description":"RU B","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	114
Details	Region: {"description":"RU C","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Site: {"description":"Important for substrate specificity","evidences":[{"source":"HAMAP-Rule","id":"MF_01989","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---