5T07
Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Decanoyl-CoA
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005886 | cellular_component | plasma membrane |
A | 0006629 | biological_process | lipid metabolic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0016790 | molecular_function | thiolester hydrolase activity |
A | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005886 | cellular_component | plasma membrane |
B | 0006629 | biological_process | lipid metabolic process |
B | 0016787 | molecular_function | hydrolase activity |
B | 0016790 | molecular_function | thiolester hydrolase activity |
B | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005886 | cellular_component | plasma membrane |
C | 0006629 | biological_process | lipid metabolic process |
C | 0016787 | molecular_function | hydrolase activity |
C | 0016790 | molecular_function | thiolester hydrolase activity |
C | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
D | 0005515 | molecular_function | protein binding |
D | 0005886 | cellular_component | plasma membrane |
D | 0006629 | biological_process | lipid metabolic process |
D | 0016787 | molecular_function | hydrolase activity |
D | 0016790 | molecular_function | thiolester hydrolase activity |
D | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 25 |
Details | binding site for residue MFK A 201 |
Chain | Residue |
A | ALA19 |
A | HOH314 |
A | HOH315 |
A | HOH335 |
A | HOH379 |
A | HOH392 |
C | TYR14 |
C | GLU53 |
C | SER127 |
C | HOH430 |
D | ALA56 |
A | GLY20 |
D | PHE57 |
D | VAL59 |
D | ARG60 |
D | PRO116 |
D | MET119 |
D | PRO121 |
A | VAL23 |
A | TYR24 |
A | HIS25 |
A | TYR66 |
A | TYR67 |
A | ALA68 |
A | PRO69 |
site_id | AC2 |
Number of Residues | 30 |
Details | binding site for residue MFK C 201 |
Chain | Residue |
B | ALA19 |
B | GLY20 |
B | VAL23 |
B | TYR24 |
B | HIS25 |
B | TYR66 |
B | TYR67 |
B | ALA68 |
B | PRO69 |
B | HOH207 |
B | HOH209 |
C | MET51 |
C | ALA56 |
C | VAL58 |
C | VAL59 |
C | ARG60 |
C | ARG86 |
C | GLY87 |
C | THR88 |
C | SER89 |
C | LEU110 |
C | PRO116 |
C | MET119 |
C | HOH301 |
C | HOH303 |
C | HOH308 |
C | HOH310 |
C | HOH313 |
C | HOH323 |
D | TYR14 |
site_id | AC3 |
Number of Residues | 29 |
Details | binding site for residue MFK D 201 |
Chain | Residue |
A | MET51 |
A | PHE57 |
A | VAL58 |
A | VAL59 |
A | ARG60 |
A | MET119 |
A | PRO121 |
B | TYR14 |
B | ALA52 |
B | GLU53 |
B | SER127 |
B | HOH273 |
D | ALA19 |
D | VAL23 |
D | TYR24 |
D | HIS25 |
D | TYR66 |
D | TYR67 |
D | ALA68 |
D | PRO69 |
D | THR102 |
D | HOH301 |
D | HOH307 |
D | HOH325 |
D | HOH335 |
D | HOH350 |
D | HOH354 |
D | HOH357 |
D | HOH367 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10041 |
Chain | Residue | Details |
A | ALA18 | |
B | ALA18 | |
C | ALA18 | |
D | ALA18 |