5T06
Crystal structure of a putative acyl-CoA thioesterase EC709/ECK0725 from Escherichia coli in complex with Hexanoyl-CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016790 | molecular_function | thiolester hydrolase activity |
| A | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016790 | molecular_function | thiolester hydrolase activity |
| B | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016790 | molecular_function | thiolester hydrolase activity |
| C | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016790 | molecular_function | thiolester hydrolase activity |
| D | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 201 |
| Chain | Residue |
| A | VAL97 |
| A | ASN98 |
| A | ASN101 |
| A | HOH315 |
| A | HOH341 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| B | TYR24 |
| B | HIS25 |
| B | HOH333 |
| B | HOH367 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| B | GLU33 |
| B | ARG36 |
| B | VAL59 |
| B | HOH311 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | binding site for residue HXC C 201 |
| Chain | Residue |
| A | VAL58 |
| A | VAL59 |
| A | ARG60 |
| A | MET119 |
| A | PRO121 |
| B | TYR14 |
| B | ALA49 |
| B | ALA52 |
| B | GLU53 |
| B | SER127 |
| B | HOH362 |
| C | GLY20 |
| C | VAL23 |
| C | TYR24 |
| C | HIS25 |
| C | TYR66 |
| C | TYR67 |
| C | ALA68 |
| C | PRO69 |
| C | THR102 |
| C | EDO202 |
| C | HOH307 |
| C | HOH325 |
| C | HOH330 |
| C | HOH333 |
| C | HOH343 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 202 |
| Chain | Residue |
| B | HIS43 |
| B | HIS44 |
| C | HXC201 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 203 |
| Chain | Residue |
| C | GLU33 |
| C | ARG36 |
| C | VAL59 |
| C | HOH337 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 201 |
| Chain | Residue |
| D | GLU33 |
| D | ARG36 |
| D | VAL59 |
| D | VAL111 |
| D | HOH301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU10041 |
| Chain | Residue | Details |
| A | ALA18 | |
| B | ALA18 | |
| C | ALA18 | |
| D | ALA18 |
