5T02
Structural characterisation of mutant Asp39Ala of thioesterase (NmACH) from Neisseria meningitidis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006637 | biological_process | acyl-CoA metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016790 | molecular_function | thiolester hydrolase activity |
| A | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006637 | biological_process | acyl-CoA metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016790 | molecular_function | thiolester hydrolase activity |
| B | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006637 | biological_process | acyl-CoA metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016790 | molecular_function | thiolester hydrolase activity |
| C | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006637 | biological_process | acyl-CoA metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016790 | molecular_function | thiolester hydrolase activity |
| D | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0006637 | biological_process | acyl-CoA metabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016790 | molecular_function | thiolester hydrolase activity |
| E | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0006637 | biological_process | acyl-CoA metabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016790 | molecular_function | thiolester hydrolase activity |
| F | 0052816 | molecular_function | long-chain fatty acyl-CoA hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue GDP A 200 |
| Chain | Residue |
| A | GLU11 |
| A | SER109 |
| A | TYR111 |
| A | ARG138 |
| C | ARG5 |
| A | TYR77 |
| A | ALA78 |
| A | ALA79 |
| A | ASN81 |
| A | GLY91 |
| A | ILE92 |
| A | ARG93 |
| A | HIS106 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | THR56 |
| A | LEU57 |
| A | GLY84 |
| A | ARG85 |
| A | THR86 |
| A | SER87 |
| C | GLN151 |
| D | GLY31 |
| D | LEU34 |
| D | LEU63 |
| D | PHE64 |
| D | LYS65 |
| D | PRO67 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | THR56 |
| D | ASN24 |
| D | GLY31 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue GDP B 201 |
| Chain | Residue |
| B | GLU11 |
| B | TYR77 |
| B | ALA78 |
| B | ALA79 |
| B | ASN81 |
| B | GLY91 |
| B | ILE92 |
| B | ARG93 |
| B | HIS106 |
| B | SER109 |
| B | TYR111 |
| B | ARG138 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue COA B 202 |
| Chain | Residue |
| B | THR56 |
| B | LEU57 |
| B | GLY84 |
| B | ARG85 |
| B | THR86 |
| B | SER87 |
| B | PRO122 |
| B | ARG146 |
| B | SER149 |
| B | LEU150 |
| C | LEU34 |
| C | PHE64 |
| C | LYS65 |
| C | GLU66 |
| C | PRO67 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 203 |
| Chain | Residue |
| B | THR56 |
| C | ASN24 |
| C | GLY31 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 204 |
| Chain | Residue |
| B | ASN24 |
| B | GLY31 |
| C | VAL55 |
| C | THR56 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue GDP C 200 |
| Chain | Residue |
| A | ARG5 |
| C | GLU11 |
| C | TYR77 |
| C | ALA78 |
| C | ALA79 |
| C | ASN81 |
| C | GLY91 |
| C | ILE92 |
| C | ARG93 |
| C | HIS106 |
| C | SER109 |
| C | TYR111 |
| C | ARG138 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue COA C 201 |
| Chain | Residue |
| B | LEU34 |
| B | LEU63 |
| B | PHE64 |
| B | LYS65 |
| B | GLU66 |
| B | PRO67 |
| C | THR56 |
| C | LEU57 |
| C | GLY84 |
| C | ARG85 |
| C | THR86 |
| C | SER87 |
| C | PRO122 |
| C | ARG146 |
| C | SER149 |
| C | LEU150 |
| site_id | AD1 |
| Number of Residues | 13 |
| Details | binding site for residue GDP D 200 |
| Chain | Residue |
| D | ARG93 |
| D | HIS106 |
| D | SER109 |
| D | TYR111 |
| D | ARG138 |
| E | ARG5 |
| D | GLU11 |
| D | TYR77 |
| D | ALA78 |
| D | ALA79 |
| D | ASN81 |
| D | GLY91 |
| D | ILE92 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue COA D 201 |
| Chain | Residue |
| A | LEU34 |
| A | PHE64 |
| A | LYS65 |
| A | GLU66 |
| A | PRO67 |
| D | VAL55 |
| D | THR56 |
| D | LEU57 |
| D | GLY84 |
| D | ARG85 |
| D | THR86 |
| D | SER87 |
| D | PRO122 |
| D | ARG146 |
| D | SER149 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 202 |
| Chain | Residue |
| A | ASN24 |
| A | GLY31 |
| D | VAL55 |
| D | THR56 |
| site_id | AD4 |
| Number of Residues | 12 |
| Details | binding site for residue GDP E 200 |
| Chain | Residue |
| D | ARG5 |
| E | GLU11 |
| E | TYR77 |
| E | ALA78 |
| E | ASN81 |
| E | GLY91 |
| E | ILE92 |
| E | ARG93 |
| E | SER109 |
| E | TYR111 |
| E | ARG138 |
| E | LYS141 |
| site_id | AD5 |
| Number of Residues | 15 |
| Details | binding site for residue COA E 201 |
| Chain | Residue |
| E | THR56 |
| E | LEU57 |
| E | GLY84 |
| E | ARG85 |
| E | THR86 |
| E | SER87 |
| E | PRO122 |
| E | ARG146 |
| E | SER149 |
| F | LEU34 |
| F | LEU63 |
| F | PHE64 |
| F | LYS65 |
| F | GLU66 |
| F | PRO67 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue CL E 202 |
| Chain | Residue |
| E | THR56 |
| F | ASN24 |
| F | GLY31 |
| site_id | AD7 |
| Number of Residues | 11 |
| Details | binding site for residue GDP F 200 |
| Chain | Residue |
| F | GLU11 |
| F | TYR77 |
| F | ALA78 |
| F | ALA79 |
| F | ASN81 |
| F | GLY91 |
| F | ILE92 |
| F | ARG93 |
| F | SER109 |
| F | TYR111 |
| F | ARG138 |
| site_id | AD8 |
| Number of Residues | 15 |
| Details | binding site for residue COA F 201 |
| Chain | Residue |
| E | LEU34 |
| E | PHE64 |
| E | LYS65 |
| E | PRO67 |
| E | ARG93 |
| E | HIS106 |
| E | ARG134 |
| F | THR56 |
| F | LEU57 |
| F | GLY84 |
| F | ARG85 |
| F | THR86 |
| F | SER87 |
| F | ARG146 |
| F | SER149 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue CL F 202 |
| Chain | Residue |
| E | ASN24 |
| E | GLY31 |
| F | VAL55 |
| F | THR56 |
