5SZV
Novel Structural Insights into GDP-Mediated Regulation of Acyl-CoA Thioesterases
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006637 | biological_process | acyl-CoA metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016790 | molecular_function | thiolester hydrolase activity |
| A | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 1900535 | biological_process | palmitic acid biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0006637 | biological_process | acyl-CoA metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016790 | molecular_function | thiolester hydrolase activity |
| B | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 1900535 | biological_process | palmitic acid biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0006637 | biological_process | acyl-CoA metabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016790 | molecular_function | thiolester hydrolase activity |
| C | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| C | 0070062 | cellular_component | extracellular exosome |
| C | 1900535 | biological_process | palmitic acid biosynthetic process |
| D | 0005829 | cellular_component | cytosol |
| D | 0006637 | biological_process | acyl-CoA metabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016790 | molecular_function | thiolester hydrolase activity |
| D | 0047617 | molecular_function | fatty acyl-CoA hydrolase activity |
| D | 0070062 | cellular_component | extracellular exosome |
| D | 1900535 | biological_process | palmitic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue COA A 201 |
| Chain | Residue |
| A | THR56 |
| A | LEU150 |
| A | HOH313 |
| A | HOH315 |
| A | HOH323 |
| A | HOH335 |
| A | HOH352 |
| A | HOH359 |
| B | VAL29 |
| B | LEU34 |
| B | PHE64 |
| A | LEU57 |
| B | LYS65 |
| B | GLU66 |
| B | PRO67 |
| B | CL201 |
| A | GLY84 |
| A | ARG85 |
| A | THR86 |
| A | SER87 |
| A | PRO122 |
| A | ARG146 |
| A | SER149 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 202 |
| Chain | Residue |
| A | ASN24 |
| A | GLY31 |
| B | THR56 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 201 |
| Chain | Residue |
| A | THR56 |
| A | COA201 |
| B | ASN24 |
| B | GLY31 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for residue COA B 202 |
| Chain | Residue |
| A | VAL29 |
| A | LEU34 |
| A | PHE64 |
| A | LYS65 |
| A | GLU66 |
| A | PRO67 |
| B | THR56 |
| B | LEU57 |
| B | GLY84 |
| B | ARG85 |
| B | THR86 |
| B | SER87 |
| B | PRO122 |
| B | ARG146 |
| B | SER149 |
| B | HOH309 |
| B | HOH350 |
| B | HOH352 |
| B | HOH353 |
| B | HOH361 |
| B | HOH381 |
| C | GLU129 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | binding site for residue COA C 201 |
| Chain | Residue |
| C | THR56 |
| C | LEU57 |
| C | GLY84 |
| C | ARG85 |
| C | THR86 |
| C | SER87 |
| C | PRO122 |
| C | ARG146 |
| C | SER149 |
| C | LEU150 |
| C | HOH302 |
| C | HOH306 |
| C | HOH307 |
| C | HOH331 |
| C | HOH340 |
| C | HOH351 |
| C | HOH352 |
| C | HOH368 |
| C | HOH371 |
| D | VAL29 |
| D | LEU34 |
| D | PHE64 |
| D | LYS65 |
| D | GLU66 |
| D | PRO67 |
| D | CL201 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | ASN24 |
| C | GLY31 |
| D | VAL55 |
| D | THR56 |
| D | COA202 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CL D 201 |
| Chain | Residue |
| C | THR56 |
| C | COA201 |
| D | ASN24 |
| D | GLY31 |
| site_id | AC8 |
| Number of Residues | 22 |
| Details | binding site for residue COA D 202 |
| Chain | Residue |
| D | THR86 |
| D | SER87 |
| D | ARG146 |
| D | LEU150 |
| D | SER153 |
| D | HOH307 |
| D | HOH315 |
| D | HOH317 |
| D | HOH328 |
| D | HOH340 |
| C | VAL29 |
| C | LEU34 |
| C | PHE64 |
| C | LYS65 |
| C | GLU66 |
| C | PRO67 |
| C | CL202 |
| C | HOH329 |
| D | THR56 |
| D | LEU57 |
| D | GLY84 |
| D | ARG85 |
