Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070301 | biological_process | cellular response to hydrogen peroxide |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 801 |
| Chain | Residue |
| A | GLY122 |
| A | ARG123 |
| A | GLY124 |
| A | SER494 |
| A | HOH1151 |
| A | HOH1473 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue CL A 802 |
| Chain | Residue |
| A | HOH1473 |
| A | GLY124 |
| A | GLU198 |
| A | VAL200 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 803 |
| Chain | Residue |
| A | GLY104 |
| A | LEU105 |
| A | TRP111 |
| A | VAL239 |
| A | PRO241 |
| A | LEU274 |
| A | GLY278 |
| A | HIS279 |
| A | GLY282 |
| A | LYS283 |
| A | THR284 |
| A | HIS285 |
| A | THR323 |
| A | SER324 |
| A | TRP330 |
| A | THR388 |
| A | CYN804 |
| A | HOH991 |
| A | HOH1033 |
| A | HOH1122 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue CYN A 804 |
| Chain | Residue |
| A | TRP111 |
| A | HIS112 |
| A | HEM803 |
| A | HOH1062 |
| A | HOH1253 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 805 |
| Chain | Residue |
| A | PRO154 |
| A | HOH1026 |
| A | HOH1419 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue MPD A 806 |
| Chain | Residue |
| A | THR323 |
| A | HOH1048 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | GLY104 |
| B | LEU105 |
| B | TRP111 |
| B | VAL239 |
| B | LEU274 |
| B | GLY278 |
| B | HIS279 |
| B | GLY282 |
| B | LYS283 |
| B | THR284 |
| B | HIS285 |
| B | THR323 |
| B | SER324 |
| B | TRP330 |
| B | THR388 |
| B | CYN804 |
| B | HOH954 |
| B | HOH987 |
| B | HOH989 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 802 |
| Chain | Residue |
| B | GLY122 |
| B | ARG123 |
| B | GLY124 |
| B | SER494 |
| B | HOH996 |
| B | HOH1450 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue CL B 803 |
| Chain | Residue |
| B | GLY124 |
| B | GLU198 |
| B | VAL200 |
| B | HOH1450 |
| B | HOH1520 |
| B | HOH1564 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue CYN B 804 |
| Chain | Residue |
| B | TRP111 |
| B | HIS112 |
| B | HEM801 |
| B | HOH1426 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue MPD B 805 |
| Chain | Residue |
| A | ALA461 |
| B | ARG506 |
| B | GLU529 |
| B | HOH950 |
| B | HOH1533 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue MPD B 806 |
| Chain | Residue |
| A | TRP362 |
| A | PHE394 |
| B | HOH1098 |
| B | HOH1119 |
| B | HOH1280 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue MPD B 807 |
| Chain | Residue |
| B | THR323 |
| B | HOH1220 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 B 808 |
| Chain | Residue |
| B | LYS380 |
| B | HIS381 |
| B | ARG382 |
| site_id | AD6 |
| Number of Residues | 10 |
| Details | |
| Chain | Residue |
| B | VAL232 |
| B | ILE107 |
| B | ARG108 |
| B | MET109 |
| B | ALA110 |
| B | HIS112 |
| B | SER113 |
| B | ALA114 |
| B | GLY115 |
| B | ALA231 |
Functional Information from PROSITE/UniProt
| site_id | PS00435 |
| Number of Residues | 11 |
| Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. TVALIAGGHTF |
| Chain | Residue | Details |
| A | THR271-PHE281 | |
| site_id | PS00436 |
| Number of Residues | 12 |
| Details | PEROXIDASE_2 Peroxidases active site signature. GGlfIRMaWHSA |
| Chain | Residue | Details |
| A | GLY103-ALA114 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-244)","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-91)","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
5SYL
