Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070301 | biological_process | cellular response to hydrogen peroxide |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue HEM A 801 |
| Chain | Residue |
| A | GLY104 |
| A | LYS283 |
| A | THR284 |
| A | HIS285 |
| A | THR323 |
| A | SER324 |
| A | THR388 |
| A | TRP420 |
| A | OXY803 |
| A | HOH940 |
| A | HOH1012 |
| A | LEU105 |
| A | HOH1068 |
| A | ILE107 |
| A | TOX111 |
| A | LEU274 |
| A | ILE275 |
| A | GLY278 |
| A | HIS279 |
| A | GLY282 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 802 |
| Chain | Residue |
| A | GLY122 |
| A | ARG123 |
| A | GLY124 |
| A | SER494 |
| A | HOH953 |
| A | HOH1120 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue OXY A 803 |
| Chain | Residue |
| A | ARG108 |
| A | TOX111 |
| A | HIS112 |
| A | ASP141 |
| A | HEM801 |
| A | HOH905 |
| A | HOH925 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue MPD A 804 |
| Chain | Residue |
| A | LEU209 |
| A | THR323 |
| A | HOH1148 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MPD A 805 |
| Chain | Residue |
| A | ASP83 |
| A | PRO154 |
| A | HOH1277 |
| A | HOH1424 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue TRS A 806 |
| Chain | Residue |
| A | ALA120 |
| A | ASP121 |
| A | ARG492 |
| A | VAL593 |
| A | LEU594 |
| A | GLU595 |
| A | LYS620 |
| A | HOH916 |
| A | HOH1082 |
| A | HOH1128 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue TRS A 807 |
| Chain | Residue |
| A | ASP60 |
| A | PRO61 |
| A | MET62 |
| A | GLY63 |
| A | HOH919 |
| A | HOH1169 |
| A | HOH1367 |
| B | PRO629 |
| B | LYS727 |
| B | ASP731 |
| B | HOH929 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | binding site for residue HEM B 801 |
| Chain | Residue |
| B | GLY104 |
| B | LEU105 |
| B | TOX111 |
| B | VAL239 |
| B | LEU274 |
| B | GLY278 |
| B | HIS279 |
| B | GLY282 |
| B | LYS283 |
| B | THR284 |
| B | HIS285 |
| B | THR323 |
| B | SER324 |
| B | TRP330 |
| B | THR388 |
| B | TRP420 |
| B | OXY803 |
| B | HOH966 |
| B | HOH1008 |
| B | HOH1116 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue NA B 802 |
| Chain | Residue |
| B | GLY122 |
| B | ARG123 |
| B | GLY124 |
| B | SER494 |
| B | HOH1064 |
| B | HOH1066 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue OXY B 803 |
| Chain | Residue |
| B | ARG108 |
| B | TOX111 |
| B | HIS112 |
| B | ASP141 |
| B | HEM801 |
| B | HOH908 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue MPD B 804 |
| Chain | Residue |
| B | VAL293 |
| B | THR323 |
| B | SER324 |
| B | HOH1447 |
| site_id | AD3 |
| Number of Residues | 9 |
| Details | binding site for residue MPD B 805 |
| Chain | Residue |
| B | GLY567 |
| B | HIS568 |
| B | ALA569 |
| B | GLU726 |
| B | HOH1171 |
| B | HOH1327 |
| B | HOH1611 |
| B | PRO250 |
| B | PHE394 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue TRS B 806 |
| Chain | Residue |
| A | PRO629 |
| A | LYS727 |
| A | ASP731 |
| A | HOH943 |
| A | HOH952 |
| B | ASP60 |
| B | PRO61 |
| B | MET62 |
| B | GLY63 |
| B | HOH939 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residue TRS B 807 |
| Chain | Residue |
| B | ALA120 |
| B | ASP121 |
| B | ARG492 |
| B | VAL593 |
| B | LEU594 |
| B | LYS620 |
| B | LEU623 |
| B | HOH937 |
| B | HOH1025 |
| B | HOH1059 |
| B | HOH1197 |
Functional Information from PROSITE/UniProt
| site_id | PS00435 |
| Number of Residues | 11 |
| Details | PEROXIDASE_1 Peroxidases proximal heme-ligand signature. TVALIAGGHTF |
| Chain | Residue | Details |
| A | THR271-PHE281 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"axial binding residue","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-91)","evidences":[{"source":"HAMAP-Rule","id":"MF_01961","evidenceCode":"ECO:0000255"}]} |
