5SWV

Dehydroquinate dehydratase and shikimate dehydrogenase from S. pombe AroM

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0003855	molecular_function	3-dehydroquinate dehydratase activity
C	0004764	molecular_function	shikimate 3-dehydrogenase (NADP+) activity
C	0005737	cellular_component	cytoplasm

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue PGE C 1601

Chain	Residue
C	GLY1128
C	LYS1270
C	ALA1271

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site_id	AC2
Number of Residues	3
Details	binding site for residue PGE C 1602

Chain	Residue
C	MET1359
C	MET1362
C	HOH1769

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor; for 3-dehydroquinate dehydratase activity => ECO:0000255|HAMAP-Rule:MF_03143

Chain	Residue	Details
C	HIS1182

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity => ECO:0000255|HAMAP-Rule:MF_03143

Chain	Residue	Details
C	LYS1211

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