5SWN

Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Fluoroacetate - Cocrystallized

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0016787	molecular_function	hydrolase activity
A	0018785	molecular_function	haloacetate dehalogenase activity
B	0003824	molecular_function	catalytic activity
B	0016787	molecular_function	hydrolase activity
B	0018785	molecular_function	haloacetate dehalogenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue FAH A 401

Chain	Residue
A	ASN110
A	ARG111
A	ARG114
A	HIS155
A	TRP156
A	TYR219

---

site_id	AC2
Number of Residues	4
Details	binding site for residue CL A 402

Chain	Residue
A	HOH616
A	ARG114
A	LEU136
A	HOH536

---

site_id	AC3
Number of Residues	3
Details	binding site for residue CL B 401

Chain	Residue
B	ASN110
B	ARG114
B	HOH622

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3R3V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Important for enzyme activity","evidences":[{"source":"PubMed","id":"21510690","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	238
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---