5SB2
DDR1, 3-chloro-N-[(1R,2S)-2-phenylcyclopropyl]-5-(1H-pyrrolo[2,3-b]pyridin-5-yloxymethyl)benzamide, 1.600A, P212121, Rfree=23.2%
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004713 | molecular_function | protein tyrosine kinase activity |
A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
A | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
site_id | PS00109 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
Chain | Residue | Details |
A | PHE756-VAL768 | |
site_id | PS00239 |
Number of Residues | 9 |
Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. NLYagdYYR |
Chain | Residue | Details |
A | ASN784-ARG792 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS766 | |
Chain | Residue | Details |
A | LEU616 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | BINDING: |
Chain | Residue | Details |
A | LYS655 | |
Chain | Residue | Details |
A | SER631 | |
Chain | Residue | Details |
A | VAL740 | |
Chain | Residue | Details |
A | ARG792 | |
A | ARG796 | |
A | ALA797 | |