5S4E
PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 Nsp3 macrodomain in complex with Z2301685688
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue DMS A 901 |
| Chain | Residue |
| A | GLY8 |
| A | PHE156 |
| A | LYS158 |
| A | HOH1106 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue W3M A 902 |
| Chain | Residue |
| A | ALA52 |
| A | PHE156 |
| A | HOH1003 |
| A | HOH1079 |
| A | HOH1085 |
| A | HOH1088 |
| A | TYR9 |
| A | LEU10 |
| A | LYS11 |
| A | ASP22 |
| A | VAL49 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue W3M A 903 |
| Chain | Residue |
| A | GLY130 |
| A | PRO136 |
| A | ASP157 |
| A | LEU160 |
| A | ASP162 |
| A | VAL165 |
| A | HOH1004 |
| A | HOH1168 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue W3M B 201 |
| Chain | Residue |
| B | LEU12 |
| B | ASP22 |
| B | ALA52 |
| B | LYS55 |
| B | ARG141 |
| B | VAL144 |
| B | PHE168 |
| B | LEU169 |
| B | HOH304 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For ADP-ribosylhydrolase activity","evidences":[{"source":"PubMed","id":"37242344","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"K9N638","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
