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5RXJ

INPP5D PanDDA analysis group deposition -- Crystal Structure of the phosphatase and C2 domains of SHIP1 in complex with Z1722836661

Functional Information from GO Data
ChainGOidnamespacecontents
A0016791molecular_functionphosphatase activity
A0046856biological_processphosphatidylinositol dephosphorylation
Functional Information from PDB Data
site_idAC1
Number of Residues9
Detailsbinding site for residue WK4 A 901
ChainResidue
ATYR440
AGLU470
AILE471
ATHR472
ASER473
ALEU620
AARG624
AGLU633
AHOH1192

site_idAC2
Number of Residues7
Detailsbinding site for residue DMS A 902
ChainResidue
AGLY531
ATHR532
ATHR579
ATHR712
AASP798
AGLN799
AHOH1226

site_idAC3
Number of Residues6
Detailsbinding site for residue DMS A 903
ChainResidue
ATYR679
ASER753
ASER754
AHIS800
ALEU802
AHOH1162

site_idAC4
Number of Residues5
Detailsbinding site for residue DMS A 904
ChainResidue
AHIS576
AHIS631
ACYS818
ATHR834
AHOH1174

227344

PDB entries from 2024-11-13

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