5RHG

PanDDA analysis group deposition -- Crystal Structure of Zika virus NS3 Helicase in complex with Z235341991

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	binding site for residue EDO A 701

Chain	Residue
A	ARG388

---

site_id	AC2
Number of Residues	9
Details	binding site for residue PO4 A 702

Chain	Residue
A	HOH987
A	GLY197
A	ALA198
A	GLY199
A	LYS200
A	THR201
A	ARG462
A	HOH816
A	HOH826

---

site_id	AC3
Number of Residues	4
Details	binding site for residue PO4 A 703

Chain	Residue
A	ARG598
A	HOH813
A	HOH825
A	HOH841

---

site_id	AC4
Number of Residues	6
Details	binding site for residue NY7 A 704

Chain	Residue
A	ALA264
A	THR265
A	SER268
A	LYS537
A	ASP540
A	PO4706

---

site_id	AC5
Number of Residues	9
Details	binding site for residue NY7 A 705

Chain	Residue
A	GLY299
A	SER302
A	THR303
A	GLU306
A	SER506
A	LEU507
A	TYR508
A	ARG509
A	HOH894

---

site_id	AC6
Number of Residues	3
Details	binding site for residue PO4 A 706

Chain	Residue
A	LYS537
A	NY7704
A	HOH925

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00541

Chain	Residue	Details
A	LEU194

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Involved in NS3 ATPase and RTPase activities => ECO:0000250|UniProtKB:P14335

Chain	Residue	Details
A	ARG456
A	ARG459

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by autolysis => ECO:0000250|UniProtKB:P06935

Chain	Residue	Details
A	ARG617

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; by host => ECO:0000269|PubMed:37478852

Chain	Residue	Details
A	LYS389

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