Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue RDV A 401 |
| Chain | Residue |
| A | ASP35 |
| A | LEU125 |
| A | ASP219 |
| A | GLY221 |
| A | THR222 |
| A | RDV402 |
| A | HOH510 |
| A | HOH513 |
| A | HOH521 |
| A | HOH675 |
| A | HOH703 |
| A | GLY37 |
| A | ILE77 |
| A | SER78 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | SER83 |
| A | PHE116 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue RDV A 402 |
| Chain | Residue |
| A | ASP15 |
| A | GLY80 |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | ILE300 |
| A | RDV401 |
| A | HOH658 |
| A | HOH660 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | ASP81 |
| A | GLY82 |
| A | SER83 |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ALA237 |
| A | GLN238 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | VAL272 |
| A | PRO274 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH529 |
| A | HOH604 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | TRP236 |
| A | ALA237 |
| A | VAL239 |
| A | SER240 |
| A | GLY241 |
| A | ALA242 |
| A | HOH526 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT A 407 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
