Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ILE183 |
| A | THR184 |
| A | TYR185 |
| A | ILE283 |
| A | SER288 |
| A | SER289 |
| A | ACT402 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 402 |
| Chain | Residue |
| A | TYR185 |
| A | SER289 |
| A | GOL401 |
| A | ILE183 |
| A | THR184 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ALA237 |
| A | GLN238 |
| A | SER240 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue RDM A 405 |
| Chain | Residue |
| A | TYR185 |
| A | THR186 |
| A | ALA187 |
| A | SER247 |
| A | ILE283 |
| A | THR324 |
| A | GOL401 |
| A | HOH518 |
| A | HOH557 |
| A | HOH625 |
| A | HOH626 |
| A | HOH640 |
| A | HOH687 |
| A | HOH701 |
| A | HOH704 |
| A | HOH718 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | VAL272 |
| A | PRO274 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH512 |
| A | HOH589 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | SER297 |
| A | ALA298 |
| A | GLY301 |
| A | ILE302 |
| A | ASN303 |
| A | HOH501 |
| A | HOH584 |
| A | HOH633 |
| A | HOH652 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | TRP236 |
| A | VAL239 |
| A | SER240 |
| A | GLY241 |
| A | ALA242 |
| A | HOH516 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 409 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue PG4 A 410 |
| Chain | Residue |
| A | ASP15 |
| A | PHE280 |
| A | PRO282 |
| A | ILE283 |
| A | NA411 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue NA A 411 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 311 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
