Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue RQD A 401 |
| Chain | Residue |
| A | ASP35 |
| A | GLY221 |
| A | THR222 |
| A | DMS402 |
| A | HOH509 |
| A | HOH679 |
| A | HOH687 |
| A | HOH694 |
| A | HOH736 |
| A | HOH743 |
| A | GLY37 |
| A | TYR79 |
| A | GLY80 |
| A | ASP81 |
| A | SER83 |
| A | PHE116 |
| A | LEU125 |
| A | ASP219 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 402 |
| Chain | Residue |
| A | ASP81 |
| A | GLY221 |
| A | THR222 |
| A | THR223 |
| A | RQD401 |
| A | HOH509 |
| A | HOH559 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | ASP81 |
| A | GLY82 |
| A | SER83 |
| A | SER113 |
| A | SER114 |
| A | SER115 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue DMS A 404 |
| Chain | Residue |
| A | VAL204 |
| A | GLY205 |
| A | SER206 |
| A | GLY207 |
| A | GLN238 |
| A | HOH718 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue DMS A 405 |
| Chain | Residue |
| A | SER46 |
| A | GLU47 |
| A | THR48 |
| A | THR49 |
| A | ALA50 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 406 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | VAL272 |
| A | PRO274 |
| A | TYR277 |
| A | ALA312 |
| A | SER329 |
| A | LYS330 |
| A | HOH530 |
| A | HOH619 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 408 |
| Chain | Residue |
| A | SER297 |
| A | ALA298 |
| A | GLY301 |
| A | ILE302 |
| A | ASN303 |
| A | HOH501 |
| A | HOH576 |
| A | HOH607 |
| A | HOH663 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 409 |
| Chain | Residue |
| A | CYS255 |
| A | ASP279 |
| A | GLY281 |
| A | CYS290 |
| A | HOH541 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue PG4 A 410 |
| Chain | Residue |
| A | ASP15 |
| A | PHE280 |
| A | ILE283 |
| A | PHE291 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | ASP35 | |
| A | SER199 | |
