Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | binding site for residue RA7 A 401 |
Chain | Residue |
A | SER233 |
A | HOH762 |
A | ALA237 |
A | ALA242 |
A | SER244 |
A | HOH651 |
A | HOH671 |
A | HOH733 |
A | HOH735 |
A | HOH745 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue DMS A 402 |
Chain | Residue |
A | GLY82 |
A | SER113 |
A | SER114 |
A | SER115 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue DMS A 403 |
Chain | Residue |
A | VAL204 |
A | GLY205 |
A | SER206 |
A | GLY207 |
A | GLN238 |
site_id | AC4 |
Number of Residues | 6 |
Details | binding site for residue DMS A 404 |
Chain | Residue |
A | ASP81 |
A | GLY221 |
A | THR222 |
A | THR223 |
A | HOH548 |
A | HOH566 |
site_id | AC5 |
Number of Residues | 8 |
Details | binding site for residue GOL A 405 |
Chain | Residue |
A | VAL272 |
A | PRO274 |
A | TYR277 |
A | ALA312 |
A | SER329 |
A | LYS330 |
A | HOH514 |
A | HOH698 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for residue GOL A 406 |
Chain | Residue |
A | SER297 |
A | ALA298 |
A | GLY301 |
A | ILE302 |
A | ASN303 |
A | HOH501 |
A | HOH551 |
A | HOH598 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue ACT A 407 |
Chain | Residue |
A | CYS255 |
A | ASP279 |
A | GLY281 |
A | CYS290 |
A | HOH526 |
A | HOH729 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue PG4 A 408 |
Chain | Residue |
A | ASP15 |
A | PHE280 |
A | ILE283 |
A | PHE291 |
A | NA409 |
site_id | AC9 |
Number of Residues | 1 |
Details | binding site for residue NA A 409 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
Chain | Residue | Details |
A | LEU32-VAL43 | |
A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | ASP35 | |
A | SER199 | |