5R69
XChem group deposition -- Crystal Structure of human YEATS4 in complex with XS038644e
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| B | GLU97 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue ZHA B 202 |
| Chain | Residue |
| B | HOH339 |
| A | ILE105 |
| B | HIS43 |
| B | HIS71 |
| B | SER73 |
| B | TYR74 |
| B | GLY92 |
| B | TRP93 |
| B | GLY94 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 601 |
| Chain | Residue |
| A | GLU137 |
| B | ARG32 |
| B | THR133 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | ARG32 |
| A | GLN46 |
| A | TRP47 |
| A | THR48 |
| A | THR89 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue ZHA A 603 |
| Chain | Residue |
| A | HIS43 |
| A | HIS71 |
| A | SER73 |
| A | TYR74 |
| A | GLY92 |
| A | TRP93 |
| A | GLY94 |
| A | HOH719 |
| B | ILE105 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Region: {"description":"Diacetylated histone H3 binding","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interacts with diacetylated histone H3","evidences":[{"source":"PubMed","id":"29900004","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30071723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5VNB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5XTZ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
