Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue RE4 A 401 |
| Chain | Residue |
| A | ASP15 |
| A | ASP119 |
| A | THR223 |
| A | RE4402 |
| A | RE4403 |
| A | HOH726 |
| A | HOH731 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue RE4 A 402 |
| Chain | Residue |
| A | TYR79 |
| A | ASP81 |
| A | SER83 |
| A | SER115 |
| A | PHE116 |
| A | ASP119 |
| A | LEU125 |
| A | RE4401 |
| A | HOH506 |
| A | HOH630 |
| A | HOH655 |
| A | ASP33 |
| A | ASP35 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue RE4 A 403 |
| Chain | Residue |
| A | TYR226 |
| A | GLY249 |
| A | PHE291 |
| A | RE4401 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue RE4 A 404 |
| Chain | Residue |
| A | LEU69 |
| A | SER71 |
| A | CYS255 |
| A | ASP279 |
| A | PRO282 |
| A | CYS290 |
| A | HOH627 |
| A | HOH722 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. LDFDTGSSDLWV |
| Chain | Residue | Details |
| A | LEU32-VAL43 | |
| A | GLY216-LEU227 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 311 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {} |
