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5QRO

PanDDA analysis group deposition -- Crystal Structure of human Brachyury in complex with Z1506050651

Functional Information from GO Data
ChainGOidnamespacecontents
A0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0045893biological_processpositive regulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue CD A 301
ChainResidue
AGLU167
AGLU167
ACYS186
ACYS186
ACD302
ACD302
AHOH450
AHOH450

site_idAC2
Number of Residues6
Detailsbinding site for residue CD A 302
ChainResidue
ACYS186
ACD301
ACD301
AHOH457
AHOH466
AGLU167

site_idAC3
Number of Residues4
Detailsbinding site for residue CD A 303
ChainResidue
ACYS122
AHOH447
AHOH459
AHOH472

site_idAC4
Number of Residues5
Detailsbinding site for residue CD A 304
ChainResidue
ALEU91
AHIS100
AHOH461
AHOH462
AHOH467

site_idAC5
Number of Residues4
Detailsbinding site for residue CD A 305
ChainResidue
ACYS122
AHOH454
AHOH472
AHOH473

site_idAC6
Number of Residues2
Detailsbinding site for residue NXJ A 306
ChainResidue
ASER89
APHE132

Functional Information from PROSITE/UniProt
site_idPS01264
Number of Residues19
DetailsTBOX_2 T-box domain signature 2. IHPDSpnfGahWMkapVsF
ChainResidueDetails
AILE125-PHE143

site_idPS01283
Number of Residues20
DetailsTBOX_1 T-box domain signature 1. LWlrFkeltNEMIVTknGRR
ChainResidueDetails
ALEU51-ARG70

222415

PDB entries from 2024-07-10

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