Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003870 | molecular_function | 5-aminolevulinate synthase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0033014 | biological_process | tetrapyrrole biosynthetic process |
| B | 0003870 | molecular_function | 5-aminolevulinate synthase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0033014 | biological_process | tetrapyrrole biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue PLP B 601 |
| Chain | Residue |
| A | THR420 |
| B | ASP357 |
| B | VAL359 |
| B | HIS360 |
| B | THR388 |
| B | LYS391 |
| B | HOH701 |
| A | THR421 |
| B | SER257 |
| B | CYS258 |
| B | PHE259 |
| B | ASN262 |
| B | HIS285 |
| B | GLU328 |
| B | SER332 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NUA B 602 |
| Chain | Residue |
| A | LEU137 |
| A | TYR138 |
| B | PRO274 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue NUA B 603 |
| Chain | Residue |
| A | LYS271 |
| A | ILE272 |
| B | SER573 |
| B | TYR574 |
| B | HOH765 |
| B | HOH785 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue NUA A 1001 |
| Chain | Residue |
| A | SER573 |
| A | TYR574 |
| B | THR268 |
| B | LYS271 |
| B | ILE272 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue PLP A 1002 |
| Chain | Residue |
| A | SER257 |
| A | CYS258 |
| A | PHE259 |
| A | ASN262 |
| A | HIS285 |
| A | GLU328 |
| A | SER332 |
| A | ASP357 |
| A | VAL359 |
| A | HIS360 |
| A | THR388 |
| A | LYS391 |
| A | HOH1101 |
| A | HOH1120 |
| B | THR420 |
| B | THR421 |
Functional Information from PROSITE/UniProt
| site_id | PS00599 |
| Number of Residues | 10 |
| Details | AA_TRANSFER_CLASS_2 Aminotransferases class-II pyridoxal-phosphate attachment site. TLGKAFGCVG |
| Chain | Residue | Details |
| B | THR388-GLY397 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"32499479","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"UniProtKB","id":"P18079","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"32499479","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"32499479","evidenceCode":"ECO:0000269"}]} |
