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5QQ5

PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with PKTTA024495b

Functional Information from GO Data
ChainGOidnamespacecontents
A0004659molecular_functionprenyltransferase activity
A0008299biological_processisoprenoid biosynthetic process
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue SO4 A 401
ChainResidue
AGLY47
AHOH603
AHOH663
AHOH674
ALYS48
ATYR49
APHE50
AARG51
AGLN91
AHOH520
AHOH525
AHOH572

site_idAC2
Number of Residues2
Detailsbinding site for residue SO4 A 402
ChainResidue
AHIS141
AHOH501

site_idAC3
Number of Residues5
Detailsbinding site for residue SO4 A 403
ChainResidue
ALEU95
ATHR163
AGLN167
ALYS207
ATYR211

site_idAC4
Number of Residues3
Detailsbinding site for residue ACT A 404
ChainResidue
AASP191
AARG237
ALEU335

site_idAC5
Number of Residues5
Detailsbinding site for residue ZN A 405
ChainResidue
AASP98
AASP102
AHOH548
AHOH589
AHOH622

site_idAC6
Number of Residues5
Detailsbinding site for residue ZN A 406
ChainResidue
AASP250
AHOH515
AHOH527
AHOH685
AHOH718

site_idAC7
Number of Residues11
Detailsbinding site for residue JJM A 407
ChainResidue
APRO197
ATYR200
ALYS201
AGLU244
ATRP276
ATHR280
AALA323
ATYR324
AHOH507
AHOH629
AHOH648

Functional Information from PROSITE/UniProt
site_idPS00444
Number of Residues13
DetailsPOLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. IGeyFQVqDDVmD
ChainResidueDetails
AILE242-ASP254

site_idPS00723
Number of Residues15
DetailsPOLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LVeDDim..DgsvmRRG
ChainResidueDetails
ALEU95-GLY109

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PDB entries from 2024-11-13

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